Page last updated: 2024-12-06

6-methyl-n-(1h-tetrazol-5-yl)-2-pyridinecarboxamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide: RN & structure given in first source; RN not in Chemline 3/84 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID54982
SCHEMBL ID17041897
MeSH IDM0120226

Synonyms (12)

Synonym
6-methyl-n-tetrazol-5-yl-2-pyridinecarboxamide
6-methyl-n-(1h-tetrazol-5-yl)-2-pyridinecarboxamide
2-pyridinecarboxamide, 6-methyl-n-tetrazol-5-yl-
brn 3614749
ta 5707f
6-methyl-n-(5h-tetrazol-5-yl)pyridine-2-carboxamide
83282-08-0
unii-b4pervzim7
SCHEMBL17041897
DTXSID801003255
6-methyl-n-(5h-tetrazol-5-yl)pyridine-2-carboximidic acid
PD160031

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" In dogs the in vivo absorption rate was similar to the in vitro dissolution rate, but in humans it was only about half."( Preparation of controlled release granules of TA-5707F using enteric polymers and ethylcellulose, and their in vivo evaluation.
Maejima, T; Matsukawa, Y; Osawa, T; Yamakita, H, 1996
)
0.29

Dosage Studied

ExcerptRelevanceReference
"Studies on controlled release dosage forms were conducted by using waxy materials for a newly developed anti-allergy drug, 6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide (TA-5707F), which is not maintained at an effective level in blood for a long duration."( Preparation of controlled release tablets of TA-5707F with wax matrix type and their in vivo evaluation in beagle dogs.
Maejima, T; Osawa, T; Yamakita, H, 1995
)
0.5
"Two types of multiple controlled release dosage forms, hydroxypropylmethyl cellulose acetyl succinate (HPMC-AS) coated granules and double layer coated granules with HPMC-AS and ethyl cellulose (EC), were prepared for the newly developed antihistaminergic drug, TA-5707F, using a centrifugal fluidizing granulator."( Preparation of controlled release granules of TA-5707F using enteric polymers and ethylcellulose, and their in vivo evaluation.
Maejima, T; Matsukawa, Y; Osawa, T; Yamakita, H, 1996
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.25

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.25 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.25)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (33.33%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (66.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]