6-alpha-methyl-progesterone profile

Description

6-alpha-methyl-progesterone: a synthetic derivative of PROGESTERONE; with anti-androgenic & synandrogenic activity [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	92847
CHEBI ID	34476
SCHEMBL ID	7978305
MeSH ID	M0074083

Synonyms (31)

Synonym
pregn-4-ene-3, 6.alpha.-methyl-
903-71-9
pregn-4-ene-3, 6-methyl-, (6.alpha.)-
nsc-75530
nsc75530
6.alpha.-methylprogesterone
6-alpha-methylprogesterone
(6alpha)-6-methylpregn-4-ene-3,20-dione
(6-alpha)-6-methylpregn-4-ene-3,20-dione
pregn-4-ene-3,20-dione, 6alpha-methyl-
pregn-4-ene-3,20-dione, 6-methyl-, (6-alpha)-
nsc 75530
6-alpha-methylpregn-3-ene-3,20-dione
pregn-4-ene-3,20-dione, 6-methyl-, (6alpha)-
pregn-4-ene-3,20-dione, 6-alpha-methyl-
6alpha-methylprogesterone
6alpha-methylpregn-4-ene-3,20-dione
6-alpha-methyl-progesterone
unii-ykt998y6uz
ykt998y6uz ,
methylprogesterone, 6.alpha.
pregn-4-ene-3,20-dione,6.alpha.-methyl-
SCHEMBL7978305
6a-methyl-4-pregnene-3 ,20-dione
CHEBI:34476
pregn-4-ene-3,20-dione, 6-methyl-, (6.alpha.)-
pregn-4-ene-3,20-dione, 6.alpha.-methyl-
6-.alpha.-methylpregn-3-ene-3,20-dione
GNFABWAPJFOZSF-KTORGGLSSA-N
Q27116095
DTXSID601294866

Drug Classes (1)

Class	Description
corticosteroid hormone	Any of a class of steroid hormones that are produced in the adrenal cortex.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	9 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Studies	Classes	Roles
phenyl acetate	[no description available]	medium	2	benzenes; phenyl acetates
cyproterone	[no description available]	medium	2	17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid; chlorinated steroid; tertiary alpha-hydroxy ketone	androgen antagonist
cyproterone acetate	[no description available]	medium	1	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; chlorinated steroid; steroid ester	androgen antagonist; geroprotector; progestin
medroxyprogesterone	[no description available]	medium	2	17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid; tertiary alpha-hydroxy ketone	contraceptive drug; progestin; synthetic oral contraceptive
flutamide	[no description available]	medium	1	(trifluoromethyl)benzenes; monocarboxylic acid amide	androgen antagonist; antineoplastic agent
medroxyprogesterone acetate	[no description available]	medium	1	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; corticosteroid; steroid ester	adjuvant; androgen; antineoplastic agent; antioxidant; female contraceptive drug; inhibitor; progestin; synthetic oral contraceptive
cortisone acetate	[no description available]	low	0	corticosteroid hormone
prednisolone acetate	[no description available]	low	0	corticosteroid hormone
norethandrolone	[no description available]	low	0	corticosteroid hormone
desoxycorticosterone acetate	[no description available]	low	0	corticosteroid hormone
triamcinolone diacetate	[no description available]	low	0	corticosteroid hormone
chlormadinone acetate	[no description available]	low	0	corticosteroid hormone
dexamethasone isonicotinate	[no description available]	low	0	corticosteroid hormone
methylprednisolone hemisuccinate	[no description available]	low	0	corticosteroid hormone; hemisuccinate
triamcinolone hexacetonide	[no description available]	low	0	corticosteroid hormone
alphadolone acetate	[no description available]	low	0	corticosteroid hormone
prednimustine	[no description available]	low	0	corticosteroid hormone
methylprednisolone aceponate	[no description available]	low	0	corticosteroid hormone
dexamethasone dipropionate	[no description available]	low	0	corticosteroid hormone
norgesterone	[no description available]	low	0	corticosteroid hormone
nomegestrol	[no description available]	low	0	corticosteroid hormone
hydrocortisone aceponate	[no description available]	low	0	corticosteroid hormone
antebate	[no description available]	low	0	corticosteroid hormone
nomegestrol acetate	[no description available]	low	0	corticosteroid hormone
diflucortolone valerate	[no description available]	low	0	corticosteroid hormone
allotetrahydrocortisol	[no description available]	low	0	corticosteroid hormone
prednisolone tebutate	[no description available]	low	0	corticosteroid hormone
11-ketoprogesterone	[no description available]	low	0	corticosteroid hormone
5-pregnene-3,20-diol	[no description available]	low	0	corticosteroid hormone
cortisol octanoate	[no description available]	low	0	corticosteroid hormone
3 alpha,17 alpha-dihydroxy-5 beta-pregnan-20-one	[no description available]	low	0	17alpha-hydroxy steroid; 20-oxo steroid; 3alpha-hydroxy steroid; C21-steroid; corticosteroid hormone	human urinary metabolite
pregnan-3,6-diol-20-one	[no description available]	low	0	corticosteroid hormone
pregnanetriol	[no description available]	low	0	corticosteroid hormone
alphaxalone	[no description available]	low	0	corticosteroid hormone
u 74006f	[no description available]	low	0	corticosteroid hormone
st 1435	[no description available]	low	0	corticosteroid hormone
23-seleno-25-homotaurocholic acid	[no description available]	low	0	corticosteroid hormone
16-hydroxyprogesterone	[no description available]	low	0	corticosteroid hormone
17 alpha-hydroxyprogesterone caproate	[no description available]	low	0	corticosteroid hormone
prednisolone 21-3-sulfobenzoate	[no description available]	low	0	corticosteroid hormone
deflazacort	[no description available]	low	0	corticosteroid hormone
hydromadinone acetate	[no description available]	low	0	corticosteroid hormone
isoflupredone acetate	[no description available]	low	0	corticosteroid hormone
19-norprogesterone	[no description available]	low	0	corticosteroid hormone
epinastine	[no description available]	low	0	corticosteroid hormone
medrysone	[no description available]	low	0	corticosteroid hormone
artisone acetate	[no description available]	low	0	corticosteroid hormone
melengestrol acetate	[no description available]	low	0	corticosteroid hormone
pregnanetriolone	[no description available]	low	0	corticosteroid hormone
corticosterone acetate	[no description available]	low	0	corticosteroid hormone
paramethasone acetate	[no description available]	low	0	corticosteroid hormone
difluprednate	[no description available]	low	0	butyrate ester; corticosteroid hormone
hydrocortisone 17-butyrate 21-propionate	[no description available]	low	0	butyrate ester; corticosteroid hormone
acepreval	[no description available]	low	0	corticosteroid hormone
LSM-33265	[no description available]	low	0	corticosteroid hormone
halobetasol	[no description available]	low	0	corticosteroid hormone
dichlorisone acetate	[no description available]	low	0	corticosteroid hormone
1-[(3S,10R,13S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone	[no description available]	low	0	corticosteroid hormone
hoe 777	[no description available]	low	0	corticosteroid hormone
ganaxolone	[no description available]	low	0	corticosteroid hormone
medrogestone	[no description available]	low	0	corticosteroid hormone
flurogestone acetate	[no description available]	low	0	corticosteroid hormone
fluocortin butyl ester	[no description available]	low	0	corticosteroid hormone
methylprednisolone sodium succinate	[no description available]	low	0	corticosteroid hormone

Condition	Relationship Strength	Studies
Body Weight	low	1
Hypomenorrhea	low	1
Irregular Menses	low	1
Irregular Menstruation	low	1
Menstrual Irregularities	low	1
Menstrual Irregularity	low	1
Menstruation Disorders	low	1
Menstruation Disturbances	low	1
Menstruation, Retrograde	low	1
Polymenorrhea	low	1

6-alpha-methyl-progesterone