Compounds > 6',7-epoxy-6,12'-dimethoxy-2,2',2'-trimethyloxyacanthanium iodide hydroiodide
Page last updated: 2024-10-15

6',7-epoxy-6,12'-dimethoxy-2,2',2'-trimethyloxyacanthanium iodide hydroiodide

Description

N,N-dimethyltrilobine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID129010947
MeSH IDM0124530

Synonyms (8)

Synonym
6',7-epoxy-6,12'-dimethoxy-2,2',2'-trimethyloxyacanthanium iodide hydroiodide
n,n-dimethyltrilobine
trilobine dimethiodide
oxyacanthanium, 6',7-epoxy-6,12'-dimethoxy-2,2',2'-trimethyl-, iodide, hydriodide, (1'alpha)-
n,n-dimethyltrilobine iodide
2h-22,26-epoxy-1,24:12,15-dietheno-6,10-metheno-16h-pyrido(2',3':17,18)(1,10)dioxacycloeicosino(2,3,4-j)isoquinoline, oxyacanthanium deriv.
dimethyltrilobine iodide
79819-99-1
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
neostigmine
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.. neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.		1.9710quaternary ammonium ionantidote to curare poisoning;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Hypertension, Renal
Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.		01.9610
Arrhythmia
[description not available]		01.9610
Arrhythmias, Cardiac
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.		01.9610
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		02.3720