5-vinyl-2'-deoxyuridine: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 148744 |
| CHEMBL ID | 221928 |
| SCHEMBL ID | 99491 |
| MeSH ID | M0057637 |
| Synonym |
|---|
| 1-((2r,4s,5r)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-vinyl-1-h-pyrimidine-2,4-dione |
| 5-vinyl-durd |
| 1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-vinyl-pyrimidine-2,4-dione |
| 5-vinyl-2'-deoxyuridine |
| 2'-deoxy-5-ethenyluridine |
| 2'-deoxy-5-vinyluridine |
| brn 0755095 |
| 5-vinyl-deoxyuridine |
| uridine, 2'-deoxy-5-vinyl- |
| CHEMBL221928 |
| 5-ethenyl-1-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
| unii-87v72at994 |
| 87v72at994 , |
| 55520-67-7 |
| SCHEMBL99491 |
| 5-vinyldeoxyuridine |
| uridine, 2'-deoxy-5-ethenyl- |
| DTXSID10970866 |
| 1-(2-deoxypentofuranosyl)-5-ethenyl-4-hydroxypyrimidin-2(1h)-one |
| Q27269846 |
| 1-((2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-vinylpyrimidine-2,4(1h,3h)-dione |
| A901366 |
| vdu (5-vinyl-2'-deoxyuridine) |
| CS-0254681 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID85559 | Concentration required to reduce the number of viral plaques in vivo cell monolayers of herpes simplex virus type 1. | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2 | Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides. |
| AID280941 | Cytotoxicity against mouse L1210/0 cells after 48 hrs | 2007 | Journal of medicinal chemistry, Apr-05, Volume: 50, Issue:7 | Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set. |
| AID84605 | Concentration required to reduce the number of viral plaques in vivo cell monolayers of herpes simplex virus type 2. | 1989 | Journal of medicinal chemistry, Feb, Volume: 32, Issue:2 | Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (7.69%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clinical cancer research : an official journal of the American Association for Cancer Research, Apr-01, Volume: 10, Issue: 7 | 2004 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clinical cancer research : an official journal of the American Association for Cancer Research, Apr-01, Volume: 10, Issue: 7 | 2004 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |