Compounds > 5-nitro-2'-deoxyuridine 5'-monophosphate
Page last updated: 2024-09-26

5-nitro-2'-deoxyuridine 5'-monophosphate

Cross-References

ID SourceID
PubMed CID149015
CHEMBL ID1234672
SCHEMBL ID9590644
MeSH IDM0068415

Synonyms (18)

Synonym
5'-uridylic acid, 2'-deoxy-5-nitro-
unii-m5xxz2mq75
m5xxz2mq75 ,
63689-79-2
5-nitro-2'-deoxyuridine 5'-monophosphate
CHEMBL1234672 ,
NDN ,
2'-deoxy-5-nitrouridine 5'-(dihydrogen phosphate)
5-nitro-2'-deoxyuridylate
[(2r,3s,5r)-3-hydroxy-5-(5-nitro-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
SCHEMBL9590644
bdbm50010241
DTXSID30213085
5-nitro-2'-deoxyuridylic acid
5-nitrodeoxyuridylic acid
Q27463760
Q27283526
PD195095

Protein Targets (4)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Thymidylate synthaseLacticaseibacillus caseiKi0.02900.01001.65509.3900AID1134942
Delta-type opioid receptorRattus norvegicus (Norway rat)Ki0.02900.00000.60689.2330AID1134942
Mu-type opioid receptorRattus norvegicus (Norway rat)Ki0.02900.00000.38458.6000AID1134942
Kappa-type opioid receptorRattus norvegicus (Norway rat)Ki0.02900.00000.18683.9500AID1134942
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1134942Competitive inhibition of thymidylate synthase purified from methotrexate-resistant Lactobacillus casei using 2'-deoxy[5-3H]uridine 5'-phosphate by radioisotope assay1979Journal of medicinal chemistry, Sep, Volume: 22, Issue:9
5-Cyano-2'-deoxyuridine 5'-phosphate: a potent competitive inhibitor of thymidylate synthetase.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
fluorodeoxyuridylate[no description available]medium20pyrimidine 2'-deoxyribonucleoside 5'-monophosphate
bromodeoxyuridylate[no description available]medium20
5-trifluoromethyl-2'-deoxyuridylic acid[no description available]medium10
5-iodo-2'-deoxyuridine 5'-monophosphate[no description available]medium10
5-chloro-2'-deoxyuridine 5'-triphosphate[no description available]medium10
bromodeoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
thymidine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
deoxyuridine[no description available]medium10pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
5-nitro-2'-deoxyuridine[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials