Compounds > 5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone
Page last updated: 2024-10-14

5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone

Description

5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone: Highly oxidized cuparene-type sesquiterpenes from a mycelial culture of Flammulina velutipes; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11288067
CHEMBL ID506541
CHEBI ID197261
MeSH IDM0377394

Synonyms (7)

Synonym
CHEMBL506541
CHEBI:197261
2-methyl-5-[(1s)-1,2,2-trimethyl-3-oxocyclopentyl]cyclohexa-2,5-diene-1,4-dione
enokipodin b
306951-08-6
5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone
DTXSID801317979
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
sesquiterpenoidAny terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (9)

Assay IDTitleYearJournalArticle
AID357012Antifungal activity against Cladosporium herbarum AHU9262 after 3 days by TLC plate assay2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357004Antimicrobial activity against Staphylococcus aureus AHU1142 at 50 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357003Antimicrobial activity against Staphylococcus aureus AHU1142 at 25 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357001Antimicrobial activity against Bacillus subtilis LMA0011 at 50 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357006Antimicrobial activity against Escherichia coli AHU1714 at 25 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357010Antimicrobial activity against Pseudomonas fluorescens AHU1719 at 50 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357000Antimicrobial activity against Bacillus subtilis LMA0011 at 25 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357009Antimicrobial activity against Pseudomonas fluorescens AHU1719 at 25 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
AID357007Antimicrobial activity against Escherichia coli AHU1714 at 50 ug/8 mm disk after 18 hrs by paper disk method2001Journal of natural products, Jul, Volume: 64, Issue:7
Antimicrobial cuparene-type sesquiterpenes, enokipodins C and D, from a mycelial culture of Flammulina velutipes.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's2 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
pentachlorophenol
PENTA: structure given in first source		210aromatic fungicide;
chlorophenol;
organochlorine pesticide;
pentachlorobenzenes		human xenobiotic metabolite
propadiene
[no description available]		2.0510allenes
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		2.0510metal allergen;
nickel group element atom;
platinum group metal atom
benzofurans
Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.		2.2510
rocaglamide
rocaglamide: RN refers to (1alpha,2alpha,3beta,3abeta,8bbeta)-isomer; isolated from stems of Aglaia elliptifolia; structure given in first source. rocaglamide : An organic heterotricyclic compound that is 2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan substituted by hydroxy groups at positions 1 and 8b, methoxy groups at positions 6 and 8, a 4-methoxyphenyl group at position 3a, a phenyl group at position 3 and a N,N-dimethylcarbamoyl group at position 1. Isolated from Aglaia odorata and Aglaia duperreana, it exhibits antineoplastic activity.		2.2510monocarboxylic acid amide;
monomethoxybenzene;
organic heterotricyclic compound		antileishmanial agent;
antineoplastic agent;
metabolite
sesquiterpenes
[no description available]		3.1750
ConditionIndicatedRelationship StrengthStudiesTrials