Page last updated: 2024-12-11

5-ht-moduline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

5-HT-moduline: isolated from rat brain; interacts specifically with HT 1B/1D receptors [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7048566
MeSH IDM0267242

Synonyms (9)

Synonym
gtpl137
5-ht-moduline
peptide1{l.s.a.l}$$$$
(2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-azaniumyl-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanoate
(2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-amino-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanoic acid
l-leucine, l-leucyl-l-seryl-l-alanyl-
169249-03-0
DTXSID20427573
PD086580
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID1346264Human 5-HT1B receptor (5-Hydroxytryptamine receptors)1998Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3
Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells.
AID1346528Human 5-HT1D receptor (5-Hydroxytryptamine receptors)1998Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3
Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells.
AID624224Allosteric regulators at Human 5-Hydroxytryptamine receptor 5-HT1B1998Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3
Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells.
AID624225Allosteric regulators at Human 5-Hydroxytryptamine receptor 5-HT1D1998Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3
Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (29)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's17 (58.62)18.2507
2000's11 (37.93)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.61 (24.57)
Research Supply Index3.50 (2.92)
Research Growth Index4.11 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (3.23%)5.53%
Reviews6 (19.35%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other24 (77.42%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]