Page last updated: 2024-12-11
5-ht-moduline
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
5-HT-moduline: isolated from rat brain; interacts specifically with HT 1B/1D receptors [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 7048566 |
MeSH ID | M0267242 |
Synonyms (9)
Synonym |
---|
gtpl137 |
5-ht-moduline |
peptide1{l.s.a.l}$$$$ |
(2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-azaniumyl-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanoate |
(2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-amino-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanoic acid |
l-leucine, l-leucyl-l-seryl-l-alanyl- |
169249-03-0 |
DTXSID20427573 |
PD086580 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1346264 | Human 5-HT1B receptor (5-Hydroxytryptamine receptors) | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3 | Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells. |
AID1346528 | Human 5-HT1D receptor (5-Hydroxytryptamine receptors) | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3 | Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells. |
AID624224 | Allosteric regulators at Human 5-Hydroxytryptamine receptor 5-HT1B | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3 | Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells. |
AID624225 | Allosteric regulators at Human 5-Hydroxytryptamine receptor 5-HT1D | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Sep, Volume: 358, Issue:3 | Specific interaction of 5-HT-moduline with human 5-HT1b as well as 5-HT1d receptors expressed in transfected cultured cells. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (29)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 17 (58.62) | 18.2507 |
2000's | 11 (37.93) | 29.6817 |
2010's | 1 (3.45) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 10.61
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (10.61) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 1 (3.23%) | 5.53% |
Reviews | 6 (19.35%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 24 (77.42%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |