Page last updated: 2024-12-08
5-heptadecylresorcinol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
5-heptadecylresorcinol : A 5-alkylresorcinol that is resorcinol which is substituted by a heptadecyl group at position 5. It is found in wheat bran. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 181700 |
| CHEMBL ID | 497530 |
| CHEBI ID | 145967 |
| SCHEMBL ID | 1914183 |
Synonyms (25)
| Synonym |
|---|
| 5-heptadecylbenzene-1,3-diol |
| CHEMBL497530 |
| 1,3-dihydroxy-5-n-heptadecylbenzene |
| CHEBI:145967 |
| 5-heptadecyl-1,3-dihydroxybenzene |
| 5-heptadecyl-1,3-benzenediol |
| 41442-57-3 |
| 5-n-heptadecylresorcinol |
| 5-heptadecylresorcinol |
| unii-mxe8zpj5xe |
| mxe8zpj5xe , |
| 1,3-benzenediol, 5-heptadecyl- |
| SCHEMBL1914183 |
| AKOS022184647 |
| LMPK15030003 |
| 5-heptadecylresorcinol, analytical standard |
| DTXSID50920522 |
| FS-9410 |
| 1,3-dihydroxy-5-heptadecylbenzene |
| AMY37952 |
| 5-heptadecyl-1,3-benzenediol; 1,3-dihydroxy-5-heptadecylbenzene; 5-heptadecylresorcinol |
| 1,3-dihydroxy-5-heptadecylbenzen; |
| A873058 |
| CS-0023110 |
| HY-N2673 |
Research Excerpts
Bioavailability
| Excerpt | Reference | Relevance |
|---|---|---|
| " However, the low bioavailability of AR-C17 due to its low water solubility restricts its application." | ( Quercetin Enhances the Availability of 5-Heptadecylresorcinol by Inhibiting the Expression of P-gp. Fan, M; Jiang, L; Li, Y; Pan, W; Qian, H; Wang, L; Zhang, K, 2023) | 1.18 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Roles (2)
| Role | Description |
|---|---|
| antineoplastic agent | A substance that inhibits or prevents the proliferation of neoplasms. |
| plant metabolite | Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Drug Classes (1)
| Class | Description |
|---|---|
| 5-alkylresorcinol | A resorcinol compound having an alkyl substituent at the 5-position. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Bioassays (6)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID376620 | Antimicrobial activity against Candida albicans ATCC 90028 by broth dilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | 5-alkylresorcinols from Merulius incarnatus. |
| AID604333 | Growth inhibition of human HCT116 cells after 48 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | 5-alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth. |
| AID376623 | Antimicrobial activity against Aspergillus fumigatus ATCC 90906 by broth dilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | 5-alkylresorcinols from Merulius incarnatus. |
| AID376621 | Antimicrobial activity against Candida glabrata ATCC 90030 by broth dilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | 5-alkylresorcinols from Merulius incarnatus. |
| AID376622 | Antimicrobial activity against Candida krusei ATCC 6258 by broth dilution method | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | 5-alkylresorcinols from Merulius incarnatus. |
| AID604334 | Growth inhibition of human HT-29 cells after 48 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry, Jul-01, Volume: 19, Issue:13 | 5-alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 8 (80.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.00
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.00) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||