Assay ID | Title | Year | Journal | Article |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
AID1763217 | Glutathione reactivity of compound at pH 9 measured by HPLC-MS assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID67529 | The compound was tested in vitro against the protozoa Entamoeba histolytica, for the inhibition of tubulin polymerization in rat brain | 2002 | Bioorganic & medicinal chemistry letters, Aug-19, Volume: 12, Issue:16
| Synthesis and antiparasitic activity of 1H-benzimidazole derivatives. |
AID75268 | The compound was tested in vitro against the protozoa Giardia lamblia, for the inhibition of tubulin polymerization in rat brain | 2002 | Bioorganic & medicinal chemistry letters, Aug-19, Volume: 12, Issue:16
| Synthesis and antiparasitic activity of 1H-benzimidazole derivatives. |
AID1785232 | Binding affinity to human TIM-3 IgV domain (residues 22 to 130) expressed in Escherichia coli BL21 (DE3) by 1H-15N SOFAST-HMQC spectroscopic analysis | 2021 | Journal of medicinal chemistry, 10-14, Volume: 64, Issue:19
| Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3). |
AID1763214 | Glutathione reactivity of compound at pH 7.5 measured by HPLC-MS assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID1763210 | Inhibition of human chymotrypsin-like beta 5i subunit of iCP using suc-LLVY-AMC as flurogenic substrate for 90 mins by fluorescence-based assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID1763216 | Glutathione reactivity of compound at pH 8.5 measured by HPLC-MS assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID1763224 | Thiol reactivity of the compound assessed as TNB2-depletion at 200 uM measured upto 24 hrs by TNB2-depletion assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID210973 | Percentage viability reduction of Trichinella spiralis muscle larvae after 3 days of incubation | 2002 | Bioorganic & medicinal chemistry letters, Aug-19, Volume: 12, Issue:16
| Synthesis and antiparasitic activity of 1H-benzimidazole derivatives. |
AID1763213 | Glutathione reactivity of compound measured after 24 hrs by NMR based assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID284279 | Antiamnesic activity against Entamoeba histolytica | 2007 | Bioorganic & medicinal chemistry, Jan-15, Volume: 15, Issue:2
| Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study. |
AID1763215 | Glutathione reactivity of compound at pH 8 measured by HPLC-MS assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID1763219 | Inhibition of beta 5 chymotrypsin-like activity (unknown origin) at 100 uM using Suc-LLVY-AMC as substrate for 90 mins by fluorescence based assay | 2021 | European journal of medicinal chemistry, Jul-05, Volume: 219 | Discovery of selective fragment-sized immunoproteasome inhibitors. |
AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |