Compounds > 5,6-dimethoxy-3H-isobenzofuran-1-one
Page last updated: 2024-12-08
5,6-dimethoxy-3H-isobenzofuran-1-one
Cross-References
Synonyms (66)
| Synonym |
|---|
| BRD-K94324294-001-02-7 |
| macconine |
| nsc25379 |
| 1(3h)-isobenzofuranone,6-dimethoxy- |
| nsc-25379 |
| 531-88-4 |
| DIVK1C_006296 |
| KBIO1_001240 |
| SDCCGMLS-0066483.P001 |
| SPECTRUM_001281 |
| BSPBIO_002564 |
| SPECTRUM5_001648 |
| AP-065/40649144 |
| 5,6-dimethoxy-2-benzofuran-1(3h)-one |
| NCGC00095581-01 |
| KBIO2_001761 |
| KBIOSS_001761 |
| KBIO2_006897 |
| KBIOGR_001841 |
| KBIO3_001784 |
| KBIO2_004329 |
| SPECTRUM3_001042 |
| SPBIO_001864 |
| SPECTRUM2_001902 |
| SPECTRUM4_001181 |
| SPECPLUS_000200 |
| SPECTRUM300062 |
| NCGC00095581-02 |
| STK234719 |
| CHEBI:113547 |
| 759409-69-3 |
| 5,6-dimethoxy-3h-isobenzofuran-1-one |
| AKOS000265096 |
| 5,6-dimethoxy-3h-2-benzofuran-1-one |
| FT-0660005 |
| AB00052752-02 |
| 5,6-dimethoxyisobenzofuran-1(3h)-one |
| A838556 |
| CHEMBL1559465 |
| metameconine |
| 5,6-dimethoxy-3 h-isobenzofuran-1-one |
| CCG-38473 |
| F3292-0464 |
| 5,6-dimethoxy-1(3h)-isobenzofuranone |
| 5,6-dimethoxyphthalide |
| 5,6-dimethoxy-phthalide |
| SCHEMBL800990 |
| 1(3h)-isobenzofuranone, 5,6-dimethoxy- |
| Q27194441 |
| 5,6-dimethoxy-3 h-isobenzofuran-1-one, aldrichcpr |
| DTXSID20282301 |
| VU0243943-3 |
| 5,6-dimethoxy-1,3-dihydro-2-benzofuran-1-one |
| SR-05000002427-1 |
| sr-05000002427 |
| meconinm |
| F11028 |
| mfcd00086313 |
| AS-10523 |
| BRD-K94324294-001-03-5 |
| 5,6-dimethoxyisobenzo[b]furan-1(3h)-one |
| 5,6-dimethoxy-3h-isobenzo[b]furan-1-one |
| BCP31068 |
| CS-0061921 |
| SY112692 |
| A923416 |
Drug Classes (1)
| Class | Description |
|---|
| 2-benzofurans | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein Targets (17)
Potency Measurements
Ceullar Components (1)
Bioassays (6)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
| AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.72
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.72 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.51 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (20.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4 (80.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |