| Assay ID | Title | Year | Journal | Article |
|---|
| AID398310 | Growth inhibition of human SKOV3 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398302 | Growth inhibition of human DMS144 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398296 | Growth inhibition of human HL-60(TB) cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398305 | Growth inhibition of human SF539 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID371779 | Inhibition of tubulin assembly | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. |
| AID552398 | Induction of apoptosis in human HL60 cells assessed as viable cells at 50 nM after24 hrs by annexin-V-PE/7-AAD staining (Rvb = 97.2%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398300 | Growth inhibition of human NCI-H460 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398298 | Growth inhibition of human HOP62 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398291 | Cytotoxicity against human A549 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID371778 | Ratio of IC50 for drug to deoxypodophyllotoxin for tubulin assembly | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. |
| AID552383 | Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552386 | Cytotoxicity against human SKOV3 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552376 | Cytotoxicity against human KB cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398306 | Growth inhibition of human SNB75 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398301 | Growth inhibition of human NCI-H522 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552569 | Induction of apoptosis in human HL60 cells assessed as viable cells at 50 nM after 48 hrs by annexin-V-PE/7-AAD staining (Rvb = 97.4%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552392 | Cytotoxicity against human HL60 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552576 | Induction of cell cycle arrest in human KB cells assessed as accumulation at subG1 phase at 50 nM after 24 hrs by propidium iodide staining-based flow cytometry (Rvb = 0.7%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID214006 | In vitro inhibitory activity against tubulin polymerization (10 uM) | 1998 | Journal of medicinal chemistry, Jun-18, Volume: 41, Issue:13
| Structure-activity requirements for flavone cytotoxicity and binding to tubulin. |
| AID552570 | Induction of apoptosis in human HL60 cells assessed as early apoptosis cells at 50 nM after 48 hrs by annexin-V-PE/7-AAD staining (Rvb = 2.5%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398311 | Growth inhibition of human UO31 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398290 | Cytotoxicity against human KB cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398299 | Growth inhibition of human NCI-H226 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398297 | Growth inhibition of human SR cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552382 | Inhibition of sheep brain tubulin polymerization after 5 mins | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID478069 | Ratio of compound IC50 to DPPT IC50 for sheep brain tubulin polymerization | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4
| Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. |
| AID398309 | Growth inhibition of human OVCAR-3 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398307 | Growth inhibition of human U251 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552379 | Induction of apoptosis in human HL60 cells assessed as induction of caspase 3/7 activation at 100 nM relative to control | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552381 | Cytotoxicity against human HT-29 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552399 | Induction of apoptosis in human HL60 cells assessed as early apoptosis cells at 50 nM after24 hrs by annexin-V-PE/7-AAD staining (Rvb = 2.6%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552587 | Induction of cell cycle arrest in human KB cells assessed as accumulation at G2/M phase at 50 nM after 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 13.8%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398304 | Growth inhibition of human SF268 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID336714 | Inhibition of tubulin assembly | 1994 | Journal of natural products, Jul, Volume: 57, Issue:7
| Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri. |
| AID552390 | Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552387 | Cytotoxicity against human A549 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552577 | Induction of cell cycle arrest in human KB cells assessed as accumulation at G0/G1phase at 50 nM after 24 hrs by propidium iodide staining-based flow cytometry (Rvb = 72.9%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552388 | Cytotoxicity against human PC3 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552571 | Induction of apoptosis in human HL60 cells assessed as late apoptosis cells at 50 nM after 48 hrs by annexin-V-PE/7-AAD staining (Rvb = 0.1%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID144650 | In vitro cytotoxic potency against NCI-60 human tumor cell line | 1998 | Journal of medicinal chemistry, Jun-18, Volume: 41, Issue:13
| Structure-activity requirements for flavone cytotoxicity and binding to tubulin. |
| AID371771 | Cytotoxicity against human KB cells at 1 uM after 72 hrs by MTS assay | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. |
| AID772624 | Displacement of [3H]colchicine from tubulin (unknown origin) | 2013 | Journal of medicinal chemistry, Sep-26, Volume: 56, Issue:18
| How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site. |
| AID398294 | Cytotoxicity against human PRMI7951 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID214689 | Inhibitory activity of the compound against tubulin polymerization | 1996 | Journal of medicinal chemistry, May-10, Volume: 39, Issue:10
| Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones. |
| AID336713 | Cytotoxicity against human KB cells | 1994 | Journal of natural products, Jul, Volume: 57, Issue:7
| Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri. |
| AID552375 | Cytotoxicity against human OVCAR8 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552393 | Cytotoxicity against human HL60R cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID214207 | In vitro inhibition of binding of [3H]colchicine to tubulin (10 uM) at compound concentration of 50 mM | 1998 | Journal of medicinal chemistry, Jun-18, Volume: 41, Issue:13
| Structure-activity requirements for flavone cytotoxicity and binding to tubulin. |
| AID552377 | Cytotoxicity against human KB cells at 10'-6 M after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552394 | Cytotoxicity against human K562 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398303 | Growth inhibition of human HCT116 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398313 | Displacement of [3H]colchicine from tubulin at 5 uM | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552380 | Inhibition of sheep brain tubulin polymerization at 2x10'-5 M after 5 mins | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552385 | Cytotoxicity against human MCF7/R cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID478065 | Induction of apoptosis in human HL60 cells assessed as increase in caspase 3/7 activation at 50 nM after 48 hrs by fluorescence assay relative to control | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4
| Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. |
| AID552578 | Induction of cell cycle arrest in human KB cells assessed as accumulation at S phase at 50 nM after 24 hrs by propidium iodide staining-based flow cytometry (Rvb = 6.9%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID214173 | In vitro inhibition of binding of [3H]colchicine to tubulin (10 uM) at compound concentration of 5 mM | 1998 | Journal of medicinal chemistry, Jun-18, Volume: 41, Issue:13
| Structure-activity requirements for flavone cytotoxicity and binding to tubulin. |
| AID552391 | Cytotoxicity against human SF268 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552389 | Cytotoxicity against human MIAPaCa2 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID214692 | Inhibitory concentration required against tubulin polymerization in the antimicrotubule activity test | 2001 | Bioorganic & medicinal chemistry letters, May-07, Volume: 11, Issue:9
| Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones. |
| AID398293 | Cytotoxicity against mouse P388 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID478063 | Cytotoxicity against human KB cells after 72 hrs by MTS assay | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4
| Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. |
| AID398312 | Inhibition of tubulin polymerization | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552584 | Induction of cell cycle arrest in human KB cells assessed as accumulation at subG1 phase at 50 nM after 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 1.2%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398295 | Cytotoxicity against human TE671 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552579 | Induction of cell cycle arrest in human KB cells assessed as accumulation at G2/M phase at 50 nM after 24 hrs by propidium iodide staining-based flow cytometry (Rvb = 19.6%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID371772 | Cytotoxicity against human KB cells after 72 hrs by MTS assay | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. |
| AID552621 | Induction of apoptosis in human HL60 cells assessed as late apoptosis cells at 50 nM after24 hrs by annexin-V-PE/7-AAD staining (Rvb = 0.2%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID478067 | Inhibition of sheep brain tubulin polymerization after 15 mins by turbidimetry | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4
| Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. |
| AID371775 | Induction of apoptosis in human HL60 cells assessed as caspase 3/7 activation at 0.1 uM relative to control | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. |
| AID398308 | Growth inhibition of human SK-MEL-5 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID398314 | Displacement of [3H]colchicine from tubulin at 50 uM | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552586 | Induction of cell cycle arrest in human KB cells assessed as accumulation at S phase at 50 nM after 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 18.4%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID552384 | Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| AID398292 | Cytotoxicity against human HCT8 cells | 1995 | Journal of natural products, Apr, Volume: 58, Issue:4
| Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra. |
| AID552585 | Induction of cell cycle arrest in human KB cells assessed as accumulation at G0/G1phase at 50 nM after 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 66.6%) | 2011 | Bioorganic & medicinal chemistry, Jan-01, Volume: 19, Issue:1
| Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |