| ID Source | ID |
|---|---|
| PubMed CID | 567982 |
| CHEMBL ID | 1344624 |
| SCHEMBL ID | 41055 |
| MeSH ID | M0196293 |
| Synonym |
|---|
| 5-(2-methylsulfanylethyl)imidazolidine-2,4-dione |
| 5-(2-methylthioethyl)hydantoin |
| 5-(2-(methylthio)ethyl)imidazolidine-2,4-dione |
| smr000061888 |
| MLS000055329 , |
| OPREA1_574916 |
| IDI1_031545 |
| SR-01000604994-2 |
| MAYBRIDGE4_000963 |
| HMS1523L17 |
| AKOS000117247 |
| 13253-44-6 |
| 5-[2-(methylthio)ethyl]hydantoin |
| M1046 |
| A806451 |
| 5-(2-methylsulfanyl-ethyl)-imidazolidine-2,4-dione |
| EN300-04385 |
| 5-[2-(methylsulfanyl)ethyl]imidazolidine-2,4-dione |
| HMS2174J09 |
| CCG-47018 |
| FT-0636857 |
| 2,4-imidazolidinedione, 5-[2-(methylthio)ethyl]- |
| AKOS017268944 |
| SCHEMBL41055 |
| dl-5-(2-methylthioethyl)hydantoin |
| CHEMBL1344624 |
| 5-(2-methylmercaptoethyl)hydantoin |
| 5-(beta-methylthioethyl)hydantoin |
| 5-[2-(methylthio)ethyl]imidazolidine-2,4-dione |
| 5-(2-methylmercaptoethyl)-hydantoin |
| 5-(beta-methylmercaptoethyl)-hydantoin |
| cid_567982 |
| bdbm39987 |
| 2,4-imidazolidinedione, 5-[2-(methylthio)ethyl]-, (.+/-.)- |
| 5-[2-(methylsulfanyl)ethyl]-2,4-imidazolidinedione # |
| Z56867181 |
| mfcd00143392 |
| AS-67729 |
| STL524725 |
| CS-0084823 |
| (r)-2-amino-2-methyl-4-pentenoicacid |
| D74568 |
| DTXSID60884585 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.6310 | 0.0447 | 17.8581 | 100.0000 | AID485341 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 8.9125 | 0.1000 | 20.8793 | 79.4328 | AID588453 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.1251 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 0.0501 | 27.0736 | 89.1251 | AID588590 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Estrogen receptor 1 | Homo sapiens (human) | IC50 (µMol) | 50.0000 | 2.1616 | 13.6892 | 26.3472 | AID713 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.19) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||