Page last updated: 2024-12-11

5-(2-iodovinyl)-1-(2'-fluoro-2'-deoxyuridine)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

5-(2-iodovinyl)-1-(2'-fluoro-2'-deoxyuridine): structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6449933
CHEMBL ID1908950
MeSH IDM0168914

Synonyms (11)

Synonym
121563-65-3
5-(2-iodovinyl)-1-(2'-fluoro-2'-deoxyuridine)
uridine, 2'-deoxy-2'-fluoro-5-(2-iodoethyenyl)-, (e)-
5-(2-iodovinyl)-1-(2-deoxy-2-fluoro-d-ribofuranosyl)uracil
1-[(2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-[(e)-2-iodovinyl]pyrimidine-2,4-dione
1-(3-fluoro-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-(2-iodo-vinyl)-1h-pyrimidine-2,4-dione
ivfru
1-[(2r,3s,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-[(e)-2-iodoethenyl]pyrimidine-2,4-dione
CHEMBL1908950
DTXSID40153302
5-(2-iodovinyl)-1-(2/'-fluoro-2/'-deoxyuridine)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (12)

Assay IDTitleYearJournalArticle
AID87993Effect on thymidine kinase in the herpes simplex type-2 infected cells1985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID87843Antiviral activity against herpes simplex type-1 expressed as ED501985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID90487Cytotoxicity expressed as ID50 which is the concentration required for 50% growth inhibition of normal human lymphocytes.1984Journal of medicinal chemistry, Jan, Volume: 27, Issue:1
Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.
AID235593Ratio of ID50/ID90 in HSV-1 infected cells1985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID87994Antiviral activity against herpes simplex type-2 expressed as ED501985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID87844Antiviral activity against herpes simplex type-1 expressed as ED901985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID235596Ratio of ID50/ID90 in HSV-2 infected cells1985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID217594In vitro antiviral activity was determined by plaque-reduction assay in HSV-2 (strain G) infected Vero cell monolayers1984Journal of medicinal chemistry, Jan, Volume: 27, Issue:1
Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.
AID217593In vitro antiviral activity was determined by plaque-reduction assay in HSV-1(strain 2931) infected Vero cell monolayers1984Journal of medicinal chemistry, Jan, Volume: 27, Issue:1
Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.
AID87842Effect on thymidine kinase in the herpes simplex type-1 infected cells1985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID218385Cytotoxic activity against vero cells was evaluated.1985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
AID87995Antiviral activity against herpes simplex type-2 expressed as ED901985Journal of medicinal chemistry, Jun, Volume: 28, Issue:6
Nucleosides. 133. Synthesis of 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)cytosines and related pyrimidine nucleosides as potential antiviral agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (33.33)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.05 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]