5-(2-bromovinyl)-2'-deoxyuridylate: RN given refers to cpd without isomeric designation [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 6505368 |
| CHEMBL ID | 1231519 |
| SCHEMBL ID | 5009511 |
| SCHEMBL ID | 4265437 |
| MeSH ID | M0118841 |
| Synonym |
|---|
| 5'-uridylic acid, 5-(2-bromoethenyl)-2'-deoxy- |
| 83378-41-0 |
| 5-(2-bromovinyl)-2'-deoxyuridylate |
| CHEMBL1231519 |
| bvdu 5'-monophosphate |
| brivudine monophosphate |
| DB04438 |
| bvdu-mp |
| brvdump |
| o7n0y11u8k , |
| 5'-uridylic acid, 5-((1e)-2-bromoethenyl)-2'-deoxy- |
| unii-o7n0y11u8k |
| 80860-82-8 |
| SCHEMBL5009511 |
| SCHEMBL4265437 |
| (e)-5-(2-bromovinyl)-2'-deoxyuridine monophosphate |
| 5-[(e)-2-bromoethenyl]-2'-deoxyuridine 5'-(dihydrogen phosphate) |
| Q27285444 |
| ((2r,3s,5r)-5-(5-((e)-2-bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID74257 | The compound was tested for inhibition of the rate of 1 uM UDP-[3H]-GlcNAc import into the lumen of the Golgi membranes. | 1996 | Journal of medicinal chemistry, Jul-19, Volume: 39, Issue:15 ISSN: 0022-2623 | Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. |
| AID87826 | Evaluation of antiviral activity against Herpes simplex virus type 2 (HSV-2) strain 196. | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID87827 | Evaluation of antiviral activity against Herpes simplex virus type 2 (HSV-2) strain G | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID87508 | Evaluation of antiviral activity against Herpes simplex virus type 1 (HSV-1) strain McIntyre | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID216539 | Evaluation of antiviral activity against Vesicular stomatitis virus. | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID74254 | Inhibitory concentration at which there is accumulation of UDP-[3H]-GlcNAc in the lumen of the Golgi membranes; Not determined | 1996 | Journal of medicinal chemistry, Jul-19, Volume: 39, Issue:15 ISSN: 0022-2623 | Inhibition of UDP-N-acetylglucosamine import into Golgi membranes by nucleoside monophosphates. |
| AID87828 | Evaluation of antiviral activity against Herpes simplex virus type 2 (HSV-2) strain Lyons | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID87507 | Evaluation of antiviral activity against Herpes simplex virus type 1 (HSV-1) strain KOS. | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID87506 | Evaluation of antiviral activity against Herpes simplex virus type 1 (HSV-1) strain F | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| AID218132 | Evaluation of antiviral activity against Vaccinia virus | 1986 | Journal of medicinal chemistry, Jul, Volume: 29, Issue:7 ISSN: 0022-2623 | Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cycloheximide | antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol | anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytomegalovirus | 0 | 1986 | 1986 | 38.0 | high | 0 | 1 | 0 | 0 | 0 | 0 | |
| Leukemia L 1210 | 0 | 1986 | 1986 | 38.0 | high | 0 | 1 | 0 | 0 | 0 | 0 |