| Assay ID | Title | Year | Journal | Article |
|---|
| AID1353892 | Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | 2018 | European journal of medicinal chemistry, Mar-25, Volume: 148 | Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors. |
| AID764734 | Inhibition of Sprague-Dawley rat brain HO-2 assessed as bilirubin formation after 60 mins by spectrophotometric analysis | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties. |
| AID764735 | Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysis | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17
| Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties. |
| AID1353891 | Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins in presence of NADPH by biliverdin reductase enzyme coupled spectrophotometric assay | 2018 | European journal of medicinal chemistry, Mar-25, Volume: 148 | Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors. |
| AID1353893 | Selectivity index, ratio of IC50 for HO-2 in Sprague-Dawley albino rat brain microsomes to IC50 for HO-1 in Sprague-Dawley albino rat spleen microsomes | 2018 | European journal of medicinal chemistry, Mar-25, Volume: 148 | Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors. |
| AID1633156 | Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by GC analysis | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. |
| AID1633155 | Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measured after 15 mins by GC analysis | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. |
| AID1799633 | Heme Oxygenase from Article 10.1111/j.1747-0285.2009.00909.x: \\Heme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-( | 2010 | Chemical biology & drug design, Jan, Volume: 75, Issue:1
| Heme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |