4-O-deacetyl vinorelbine: active metabolite of vinorelbine [MeSH]
ID Source | ID |
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PubMed CID | 21783126 |
CHEMBL ID | 537777 |
MeSH ID | M0510816 |
Synonym |
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CHEMBL537777 |
xkd4u87szy , |
o-deacetylnavelbine |
unii-xkd4u87szy, xkd4u87szy, 4-o-deacetylvinorelbine |
DTXSID10925513 |
4-o-deacetyl vinorelbine |
vinorelbine tartrate impurity b [ep impurity] |
aspidospermidine-3-carboxylic acid, 6,7-didehydro-15-((2r,6r,8s)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2h-azecino(4,3-b)indol-8-yl)-3,4-dihydroxy-16-methoxy-1-methyl-, methyl ester, (2.beta.,3.beta.,4.beta.,5.alpha.,12r,19.alpha.)- |
o4-deacetyl-4-deoxy-3,4-didehydro-8-norvincaleukoblastine |
4-o-deacetylvinorelbine |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
bis(4-nitrophenyl)phosphate | aryl phosphate | 2012 | 2012 | 12.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | ||
loperamide | monocarboxylic acid amide; monochlorobenzenes; piperidines; tertiary alcohol | anticoronaviral agent; antidiarrhoeal drug; mu-opioid receptor agonist | 2012 | 2012 | 12.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |
interleukin-8 | 2016 | 2016 | 8.0 | high | 0 | 0 | 0 | 0 | 1 | 0 | |||
nitrophenols | 2012 | 2012 | 12.0 | high | 0 | 0 | 0 | 0 | 1 | 0 |
Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
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Article | Year |
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Cellular and molecular effects of metronomic vinorelbine and 4-O-deacetylvinorelbine on human umbilical vein endothelial cells. Anti-cancer drugs, , Volume: 27, Issue:3 | 2016 |