| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
nitrites
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed) | 2.05 | 1 | 0 | monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species | human metabolite |
benzonitrile
benzonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group. | 2.39 | 2 | 0 | benzenes;
nitrile | |
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent. | 7.06 | 1 | 0 | isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
azomycin
azomycin: RN given refers to parent cpd with specified locant; structure | 2.05 | 1 | 0 | C-nitro compound;
imidazoles | antitubercular agent |
3-nitrobenzonitrile
[no description available] | 1.99 | 1 | 0 | | |
4-cyanophenol
4-cyanophenol: reversible monoamine oxidase inhibitor | 1.98 | 1 | 0 | phenols | EC 1.4.3.4 (monoamine oxidase) inhibitor |
nitroxinil
Nitroxinil: Proposed anthelmintic for fasciola and liver fluke infestations. | 1.98 | 1 | 0 | | |
4-methoxybenzonitrile
4-methoxybenzonitrile: RN given refers to parent cpd | 1.99 | 1 | 0 | | |
3-methoxybenzonitrile
3-methoxybenzonitrile: RN & N1 from 9th CI Form Index; RN given refers to unlabeled parent cpd | 1.99 | 1 | 0 | | |
pa 824
pretomanid: nitroimidazopyran derived from 5-nitroimidazoles; a prodrug that requires activation by a bacterial F420-depedent glucose-6-phosphate dehydrogenase (Fgd) and nitroreductase to activate components that then inhibit bacterial mycolic acid and protein synthesis; structure in first source | 2.05 | 1 | 0 | | |