Compounds > 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene
Page last updated: 2024-12-07

4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene: bisphenol A metabolite; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID83494
CHEBI ID31129
SCHEMBL ID3419256
MeSH IDM0490804

Synonyms (21)

Synonym
4,4'-(4-methylpent-1-ene-2,4-diyl)diphenol
4-methyl-2,4-bis-(p-hydroxyphenyl)pent-1-ene
C13625 ,
13464-24-9
4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene
4-[4-(4-hydroxyphenyl)-4-methylpent-1-en-2-yl]phenol
unii-tz5ywx57vv
4-methyl-2,4-bis(p-hydroxyphenyl)pent-1-ene
tz5ywx57vv ,
phenol, 4,4'-(1,1-dimethyl-3-methylene-1,3-propanediyl)bis-
AKOS024324168
phenol,4,4'-(1,1-dimethyl-3-methylene-1,3-propanediyl)bis-
SCHEMBL3419256
DTXSID0065482
CHEBI:31129
MZLYLGGRVAFGBY-UHFFFAOYSA-N
2-methyl-4-pentene, 2,4-bis(4-hydroxyphenyl)-
4-[3-(4-hydroxyphenyl)-3-methyl-1-methylene-butyl]phenol
2,4-bis(4-hydroxyphenyl)-4-methyl-1-pentene
Q4637168
phenol, 4,4'-(1,1-dimethyl-3-methylenetrimethylene)di-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
phenolsOrganic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (15)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's7 (46.67)24.3611
2020's7 (46.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.36

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.36 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index5.19 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.36)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
4-nonylphenol
4-nonylphenol: structure in first source; see also record for nonylphenol. 4-nonylphenol : A member of the class of phenols that is phenol which is para-substituted with a nonyl group.		2.5920phenolsenvironmental contaminant
bisphenol a
4,4'-isopropylidene diphenol: stimulates proliferative responses and cytokine productions of murine spleen cells and thymus cells in vitro. bisphenol : By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom.. bisphenol A : A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.		3.91110bisphenolendocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen
4-tert-octylphenol
4-tert-octylphenol: structure given in first source		2.8530alkylbenzene
cyclopentane
Cyclopentanes: A group of alicyclic hydrocarbons with the general formula R-C5H9.. cyclopentanes : Cyclopentane and its derivatives formed by substitution.		2.3110cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
dihydrotestosterone
Dihydrotestosterone: A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.. 17beta-hydroxyandrostan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with unspecified configuration at position 5.. 17beta-hydroxy-5alpha-androstan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5.		2.151017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3h-cyclopenta(c)quinolin-8-yl)ethanone
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone: G-1 was able to induce both c-fos expression and proliferation in the ERalpha-negative/GPR30-positive SKBR3 breast cancer cells, the requirement for ERalpha expression in GPR30/EGFR signaling may depend on the specific cellular context of different tumor types		2.3110agonist
cytochrome c-t
Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.		2.3110
ConditionIndicatedRelationship StrengthStudiesTrials
Breast Cancer
[description not available]		07.8220
Breast Neoplasms
Tumors or cancer of the human BREAST.		02.8220
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		02.0210