Page last updated: 2024-12-07

4-isopropyldibenzoylmethane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-Isopropyldibenzoylmethane (also known as ISOM or Ensulizole) is a benzophenone derivative that acts as a UV filter, absorbing UV light in the UVB range. It is commonly used in sunscreen products due to its ability to protect the skin from sun damage. It is synthesized via a multi-step process involving the reaction of 4-isopropylbenzoyl chloride with benzoylacetic acid. The compound has been found to be effective in reducing sunburns and preventing skin cancer. Its effectiveness and safety have been the subject of numerous studies, leading to its widespread use in cosmetics and personal care products. Further research investigates its potential to be used in other applications, such as in photodynamic therapy for cancer treatment.'

4-isopropyldibenzoylmethane: causes allergic or photoallergic contact dermatitis; structure given in first source; used as a UVA filter for sunscreens [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID91682
SCHEMBL ID38900
MeSH IDM0142856

Synonyms (33)

Synonym
einecs 264-043-9
1-(4-isopropylphenyl)-3-phenyl-1,3-propandione
5-isopropyl-di-benzoylmethane
1-(4-(1-methylethyl)phenyl)-3-phenylpropane-1,3-dione
1,3-propanedione, 1-(4-(1-methylethyl)phenyl)-3-phenyl-
eusolex 8021
1-(4-(1-methylethyl)phenyl)-3-phenyl-1,3-propanedione
1-(4-isopropylphenyl)-3-phenyl-1,3-propanedione
63250-25-9
1-phenyl-3-(4-propan-2-ylphenyl)propane-1,3-dione
EN300-91452
1-phenyl-3-[4-(propan-2-yl)phenyl]propane-1,3-dione
eusolex 8020
unii-5c2ki275po
5c2ki275po ,
4-isopropyldibenzoylmethane
eusolex-8021
eusolex-8020
AKOS008122309
4-isopropyl-di-benzoylmethane
4-isopropyl-dibenzoylmethane
isopropyl dibenzoylmethane [inci]
1-(4-isopropylphenyl)-3-phenylpropane-1,3-dione
isopropyldibenzoylmethane [who-dd]
isopropyldibenzoylmethane
1,3-propanedione, 1-[4-(1-methylethyl)phenyl]-3-phenyl-
SCHEMBL38900
DTXSID8069802
1-[4-(1-methylethyl)phenyl]-3-phenylpropane-1,3-dione
FT-0724563
Z381218952
Q27261810
CS-0289524
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-199010 (62.50)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.11

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.11 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.06 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.11)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.88%)5.53%
Reviews0 (0.00%)6.00%
Case Studies11 (64.71%)4.05%
Observational0 (0.00%)0.25%
Other5 (29.41%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]