| Assay ID | Title | Year | Journal | Article |
|---|
| AID5626 | Inhibitory constant against cloned human 5-hydroxytryptamine 2C receptor using with [125I]- DOI radioligand | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID295911 | Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization relative to 5HT | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID1442366 | Invivo agonist activity at 5HT2A in ip dosed DOM-trained Sprague-Dawley rat assessed as increase in discriminative stimulus pretreated before testing | 2017 | Journal of medicinal chemistry, 04-13, Volume: 60, Issue:7
| The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. |
| AID258818 | Head twitch response in SD mice, sc | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID1442367 | Invivo agonist activity at 5HT2A in DOM-trained rhesus monkey assessed as increase in discriminative stimulus administered subcutaneously pretreated before testing | 2017 | Journal of medicinal chemistry, 04-13, Volume: 60, Issue:7
| The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. |
| AID258814 | Ratio of permeability from basolateral to apical over apical to basolateral side of the MDCK cell transfected with human MDR1 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID188584 | Number of rats responding out of 5 treated rats at a dose of 0.5 mg/Kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID258811 | Distribution coefficient at pH 7.4 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID258787 | Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar rats | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID295914 | Distribution coefficient, log D at pH 7.4 | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID175412 | Dose required to produce 50% hallucinogenic potency in rat was determined at a dose of 0.125 mg/kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID5270 | Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligand | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID258812 | Permeability from apical to basolateral side of the MDCK cell transfected with human MDR1 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID258824 | Lowering of intraocular pressure in lasered cynomolgus monkey after 6 hrs at 100 ug | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID251439 | Percent reduction of intraocular pressure after 3 hours following topical ocular administration to normal eye conscious cynomolgus monkeys | 2004 | Journal of medicinal chemistry, Nov-18, Volume: 47, Issue:24
| Beta-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. |
| AID295910 | Displacement of [125I]DOI from 5HT2A receptor in rat cerebral cortex | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID258817 | Ratio of passive diffusion permeability from basolateral to apical over apical to basolateral side of the MDCK cell transfected with MDR1 in presence of cyclosporin A | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID5240 | Binding affinity to 5-hydroxytryptamine 2 receptor of rat cortical membranes using [3H]- DOB; ND means no data. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID126793 | Tested for the ability to lower IOP in conscious cynomolgus monkeys with laser-induced ocular hypertension after 1 hr postdose of the compound | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID3695 | Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID5770 | Inhibitory constant against cloned human 5-hydroxytryptamine 2B receptor using with [125I]- DOI radioligand | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258816 | Passive diffusion permeability from basolateral to apical side of the MDCK cell transfected with human MDR1 in presence of cyclosporin A | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID188585 | Number of rats responding out of 5 treated rats at a dose of 0.75 mg/Kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID1830039 | Displacement of [3H]LSD from human recombinant 5-HT2C receptor expressed in HEK cells by radioligand completion assay relative to control | 2021 | Journal of medicinal chemistry, 09-23, Volume: 64, Issue:18
| Activity of |
| AID188583 | Number of rats responding out of 5 treated rats at a dose of 0.25 mg/Kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID4096 | Evaluated for the binding affinity to hippocampus striatal membranes at 5-hydroxytryptamine 1A receptor binding site by using [3H]-8-OH- DPAT as a radioligand. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID6405 | Binding affinity at rat 5-hydroxytryptamine receptor. | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID295916 | Agonist activity at 5HT2A receptor in rat A7r5 cells assessed as intracellular calcium mobilization | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID126794 | Tested for the ability to lower IOP in conscious cynomolgus monkeys with laser-induced ocular hypertension after 3h postdose of the compound | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID251437 | Percent reduction of intraocular pressure after 1 hour following topical ocular administration to normal eye conscious cynomolgus monkeys | 2004 | Journal of medicinal chemistry, Nov-18, Volume: 47, Issue:24
| Beta-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. |
| AID175415 | Dose required to produce 50% hallucinogenic potency in rat was determined at a dose of 0.25 mg/kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID4764 | Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 1C receptor binding site by using [3H]- MES as a radioligand. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID295915 | Reduction of intra ocular pressure in cynomolgus monkey at 300 ug | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID5471 | In vitro efficacy against rat 5-hydroxytryptamine 2A receptor was determined by using CA+ assay (Emax) | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258823 | Lowering of intraocular pressure in lasered cynomolgus monkey after 3 hrs at 100 ug | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID5571 | In vitro inhibitory constant against [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortex | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258790 | Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID5299 | Displacement of [3H]ketanserin from rat prefrontal cortex 5-hydroxytryptamine 2 receptor | 1986 | Journal of medicinal chemistry, Feb, Volume: 29, Issue:2
| 5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues. |
| AID295917 | Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID251440 | Percent reduction of intraocular pressure after 6 hours following topical ocular administration to normal eye conscious cynomolgus monkeys | 2004 | Journal of medicinal chemistry, Nov-18, Volume: 47, Issue:24
| Beta-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. |
| AID258789 | Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID175418 | Dose required to produce 50% hallucinogenic potency in rat was determined at a dose of 0.75 mg/kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID258786 | Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID4699 | Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID295912 | Agonist activity at 5HT2B receptor in rat stomach fundus assessed as intracellular calcium mobilization relative to 5HT | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID5472 | In vitro efficacy against rat 5-hydroxytryptamine 2A receptor determined by using PI assay (Emax) | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258788 | Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID176716 | Dose at which the rats perform 50% appropriate drug -lever responding was determined | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID3696 | Binding affinity for 5-hydroxytryptamine 1 receptor of rat prefrontal cortex | 1986 | Journal of medicinal chemistry, Feb, Volume: 29, Issue:2
| 5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogues. |
| AID126795 | Tested for the ability to lower IOP in conscious cynomolgus monkeys with laser-induced ocular hypertension after 6 hr postdose of the compound | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258785 | Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortex | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID5487 | In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortex | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID295913 | Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HT | 2007 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 17, Issue:11
| Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. |
| AID1830038 | Displacement of [3H]LSD from human recombinant 5-HT2B receptor expressed in CHO cells by radioligand completion assay relative to control | 2021 | Journal of medicinal chemistry, 09-23, Volume: 64, Issue:18
| Activity of |
| AID5159 | Inhibitory constant against cloned human 5-hydroxytryptamine 2A receptor using with [125I]- DOI radioligand | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258791 | Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID3590 | In vitro inhibitory concentration required against [3H]8-OH-DPAT binding to cloned human 5-hydroxytryptamine 1A receptor | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID1830042 | Displacement of [3H]5-CT from human recombinant 5-HT7A receptor expressed in HEK cells by radioligand completion assay | 2021 | Journal of medicinal chemistry, 09-23, Volume: 64, Issue:18
| Activity of |
| AID1830041 | Displacement of [3H]LSD from human recombinant 5-HT2A receptor expressed in HEK cells by radioligand completion assay relative to control | 2021 | Journal of medicinal chemistry, 09-23, Volume: 64, Issue:18
| Activity of |
| AID1830044 | Displacement of [3H]8-OH-DAPT from human recombinant 5-HT1A receptor expressed in HEK cells measured after 60 to 90 mins by radioligand completion assay relative to control | 2021 | Journal of medicinal chemistry, 09-23, Volume: 64, Issue:18
| Activity of |
| AID258813 | Permeability from basolateral to apical side of the MDCK cell transfected with human MDR1 | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID175417 | Dose required to produce 50% hallucinogenic potency in rat was determined at a dose of 0.5 mg/kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID258822 | Lowering of intraocular pressure in lasered cynomolgus monkey after 1 hr at 100 ug | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID5473 | The receptor (5-hydroxytryptamine 2A ) mediated mobilization of intracellular calcium [Ca2+] was studied in rat smooth muscle cells | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID188580 | Number of rats responding out of 5 treated rats at a dose of 0.125 mg/Kg | 1982 | Journal of medicinal chemistry, Oct, Volume: 25, Issue:10
| Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane. |
| AID5464 | In vitro relative agonist activity against 5-hydroxytryptamine 2A using PI assay in rat vascular smooth muscle cells | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID5275 | Evaluated for the binding affinity to rat frontal cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- KET as a radioligand;ND means no data | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Central serotonin receptors as targets for drug research. |
| AID3519 | Tested for functional response on CHO cells expressing cloned human 5-hydroxytryptamine 1A receptor | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID258815 | Passive diffusion permeability from apical to basolateral side of the MDCK cell transfected with human MDR1 in presence of cyclosporin A | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| 1-((S)-2-aminopropyl)-1H-indazol-6-ol: a potent peripherally acting 5-HT2 receptor agonist with ocular hypotensive activity. |
| AID1346893 | Human 5-HT2C receptor (5-Hydroxytryptamine receptors) | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID1346867 | Human 5-HT2B receptor (5-Hydroxytryptamine receptors) | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID624216 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2C | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID1346867 | Human 5-HT2B receptor (5-Hydroxytryptamine receptors) | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID624216 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2C | 1999 | Journal of neurochemistry, May, Volume: 72, Issue:5
| High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action. |
| AID624219 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2B | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID624216 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2C | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID1259419 | Human 5-HT2A receptor (5-Hydroxytryptamine receptors) | 1998 | Journal of medicinal chemistry, Dec-17, Volume: 41, Issue:26
| A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor. |
| AID1259419 | Human 5-HT2A receptor (5-Hydroxytryptamine receptors) | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID624219 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2B | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID624219 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2B | 1998 | Journal of medicinal chemistry, Dec-17, Volume: 41, Issue:26
| A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor. |
| AID1346893 | Human 5-HT2C receptor (5-Hydroxytryptamine receptors) | 1999 | Journal of neurochemistry, May, Volume: 72, Issue:5
| High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action. |
| AID624235 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2A | 1998 | Journal of medicinal chemistry, Dec-17, Volume: 41, Issue:26
| A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor. |
| AID1259419 | Human 5-HT2A receptor (5-Hydroxytryptamine receptors) | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID1346867 | Human 5-HT2B receptor (5-Hydroxytryptamine receptors) | 1998 | Journal of medicinal chemistry, Dec-17, Volume: 41, Issue:26
| A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor. |
| AID1346893 | Human 5-HT2C receptor (5-Hydroxytryptamine receptors) | 1999 | Naunyn-Schmiedeberg's archives of pharmacology, Jan, Volume: 359, Issue:1
| Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors. |
| AID624235 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2A | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID624216 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2C | 1999 | Naunyn-Schmiedeberg's archives of pharmacology, Jan, Volume: 359, Issue:1
| Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors. |
| AID1346893 | Human 5-HT2C receptor (5-Hydroxytryptamine receptors) | 2004 | Naunyn-Schmiedeberg's archives of pharmacology, Aug, Volume: 370, Issue:2
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. |
| AID624235 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT2A | 2003 | Journal of medicinal chemistry, Sep-11, Volume: 46, Issue:19
| A novel and selective 5-HT2 receptor agonist with ocular hypotensive activity: (S)-(+)-1-(2-aminopropyl)-8,9-dihydropyrano[3,2-e]indole. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |