| Assay ID | Title | Year | Journal | Article |
|---|
| AID719719 | Inhibition of human CPT1B | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID1269394 | Inhibition of wild type amyloid beta (1 to 42) (unknown origin) aggregation at 50 uM by Thioflavin-T fluorescence assay | 2016 | Bioorganic & medicinal chemistry, Jan-15, Volume: 24, Issue:2
| Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids. |
| AID719671 | Inhibition of rat FAO | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID188648 | Pyruvate dehydrogenase activity in vivo was measured following subcutaneous administration of 1.2 mmol/kg | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID157200 | Concentration required for 50% Inhibition of activity against Protein Tyrosine Phosphatases 1B | 2002 | Journal of medicinal chemistry, Aug-29, Volume: 45, Issue:18
| Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases. |
| AID191943 | Percent Stimulation of pyruvate oxidation in rat diaphragm was measured at 2 mM concentration of DCA (dichloroacetic acid) | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID191932 | Tested for pyruvate oxidation in rat diaphragm, measured as % conversion of [14C]pyruvate to 14CO2 at 5 mM concentration | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID165331 | Concentration required for 50% Inhibition of activity against Protein-tyrosine phosphatase Lar | 2002 | Journal of medicinal chemistry, Aug-29, Volume: 45, Issue:18
| Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases. |
| AID719695 | Inhibition of CPT1B in liver mitochondria | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID191942 | Percent Stimulation of pyruvate oxidation in rat diaphragm by the compound was measured at 2 mM concentration | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID719674 | Inhibition of human CPT2 | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID719673 | Inhibition of human FAO | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID1269387 | Drug level treated with kaempferol after 4 hrs by LC/Q Tof-MS/MS analysis | 2016 | Bioorganic & medicinal chemistry, Jan-15, Volume: 24, Issue:2
| Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids. |
| AID164859 | Concentration required for 50% Inhibition of activity against Yersinia Protein-tyrosine phosphatase | 2002 | Journal of medicinal chemistry, Aug-29, Volume: 45, Issue:18
| Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases. |
| AID719698 | Inhibition of rat CPT2 | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID719720 | Inhibition of human CPT1A | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID719672 | Cytotoxicity in human KB cells | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| AID1269372 | Binding affinity to HFIP-treated 15N-labelled wild type Amyloid beta (1 to 42) monomer (unknown origin) assessed as change in chemical shifts at 500 uM after 1 hr by NMR analysis | 2016 | Bioorganic & medicinal chemistry, Jan-15, Volume: 24, Issue:2
| Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids. |
| AID191928 | Tested for pyruvate oxidation in rat diaphragm, measured as % conversion of [14C]pyruvate to 14CO2 at 0.5 mM concentration of DCA (dichloroacetic acid) | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID188645 | Pyruvate dehydrogenase active/ Pyruvate dehydrogenase total was measured by sc administering the DCA in rat at a dose of 1.2 mmol/kg | 1981 | Journal of medicinal chemistry, Apr, Volume: 24, Issue:4
| Promotion of carbohydrate oxidation in the heart by some phenylglyoxylic acids. |
| AID1269388 | Inhibition of nucleation phase of HFIP-treated 15N-labelled wild type Amyloid beta (1 to 42) (unknown origin) assessed as time required for nucleation at 50 uM by Thioflavin-T fluorescence assay in presence of fibril seed (Rvb = 1 to 4 hrs) | 2016 | Bioorganic & medicinal chemistry, Jan-15, Volume: 24, Issue:2
| Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids. |
| AID719697 | Inhibition of CPT1B in heart mitochondria | 2011 | Journal of medicinal chemistry, May-12, Volume: 54, Issue:9
| Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |