4-hydroxymexiletine: mexiletine metabolite; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 93286 |
| CHEBI ID | 173536 |
| MeSH ID | M0133029 |
| Synonym |
|---|
| 53566-99-7 |
| 4-(2-aminopropoxy)-3,5-dimethylphenol |
| CHEBI:173536 |
| p-hydroxymexiletine |
| phenol, 4-(2-aminopropoxy)-3,5-dimethyl- |
| d9m8aq3ndj , |
| 4-hydroxymexiletine |
| para-hydroxymexiletine |
| unii-d9m8aq3ndj |
| YWOSWRCXWBDSRQ-UHFFFAOYSA-N |
| 4-(2-aminopropoxy)-3,5-dimethylphenol # |
| DTXSID60968334 |
| ko 2127 |
| phenol,4-(2-aminopropoxy)-3,5-dimethyl- |
| Excerpt | Reference | Relevance |
|---|---|---|
| " There were no significant differences in elimination half-life (t1/2) and mean residence time (MRT) for mexiletine and its metabolites." | ( Pharmacokinetics of mexiletine and its metabolites, hydroxymethylmexiletine and p-hydroxymexiletine, after single oral administration in healthy subjects. Filipek, M; Koliński, P; Paczkowski, D; Sadowski, Z, ) | 0.13 |
| Class | Description |
|---|---|
| phenols | Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. |
| aromatic ether | Any ether in which the oxygen is attached to at least one aryl substituent. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.16) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||