4-hydroxy-equilin: structure given in first source; metabolite of EQUILIN; induces DNA damage [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 133729 |
| MeSH ID | M0179458 |
| Synonym |
|---|
| 4-hydroxy-equilin |
| 4-hydroxyequilin |
| 81608-62-0 |
| estra-1,3,5(10),7-tetraen-17-one, 3,4-dihydroxy- |
| 3,4-dihydroxyestra-1,3,5(10),7-tetraen-17-one |
| DTXSID901002086 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " An immunoassay with 4OHEN-1 revealed a linear dose-response between known amounts of 4-OHEN-DNA adducts and the antibody binding to those adducts, with a detection limit of approximately five adducts/10(8) bases in 1 microg DNA sample." | ( Quantitative detection of 4-hydroxyequilenin-DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody. Itoh, S; Iwamoto, T; Mori, T; Nishiwaki, T; Okahashi, Y; Shibutani, S; Sugiura, S; Suzuki, N; Ueno, S, 2010) | 0.36 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||