Page last updated: 2024-11-07

4-hydroxy-3-nitrophenylacetyl-o-succinimide ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1-((4-hydroxy-3-nitrophenyl)acetoxy)pyrrolidine-2,5-dione : The ester formed between N-hydroxysuccinimide and (4-hydroxy-3-nitrophenyl)acetic acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID126530
CHEBI ID55341
SCHEMBL ID13702252
MeSH IDM0087324

Synonyms (22)

Synonym
np-o-su
4-hydroxy-3-nitrobenzeneacetic acid, 2,5-dioxo-1-pyrrolidinyl ester
CHEBI:55341 ,
4-hydroxy-3-nitrobenzeneacetic acid 2,5-dioxo-1-pyrrolidinyl ester
1-[[(4-hydroxy-3-nitrophenyl)acetyl]oxy]-2,5-pyrrolidinedione
1-((4-hydroxy-3-nitrophenyl)acetoxy)pyrrolidine-2,5-dione
4-hydroxy-3-nitrophenylacetyl-o-succinimide ester
np-o-succinimide ester
np-o-succinimide
1-[2-(4-hydroxy-3-nitrophenyl)acetoxy]pyrrolidine-2,5-dione
75679-31-1
1-((4-hydroxy-3-nitrophenyl)acetoxy)-2,5-pyrrolidinedione
(2,5-dioxopyrrolidin-1-yl) 2-(4-hydroxy-3-nitrophenyl)acetate
2,5-pyrrolidinedione, 1-(((4-hydroxy-3-nitrophenyl)acetyl)oxy)-
EPITOPE ID:116657
SCHEMBL13702252
1-([(4-hydroxy-3-nitrophenyl)acetyl]oxy)-2,5-pyrrolidinedione #
WXEZCVSZMLAVNV-UHFFFAOYSA-N
1-{[(4-hydroxy-3-nitrophenyl)acetyl]oxy}pyrrolidine-2,5-dione
DTXSID70997110
Q27124244
2,5-dioxopyrrolidin-1-yl 2-(4-hydroxy-3-nitrophenyl)acetate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
haptenAny substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
N-hydroxysuccinimide esterAn ester of N-hydroxysuccinimide.
2-nitrophenolsA mononitrophenol that is 2-nitrophenol and its derivatives resulting from substitution of one or more of the hydrogens attached to the benzene ring by a non-nitro group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (60.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.70

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.70 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.09 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.70)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]