Compounds > 4-diphosphocytidyl-2-c-methylerythritol
Page last updated: 2024-11-13

4-diphosphocytidyl-2-c-methylerythritol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-diphosphocytidyl-2-C-methylerythritol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

4-CDP-2-C-methyl-D-erythritol(2-) : Dianion of 4-CDP-2-C-methyl-D-erythritol arising from deprotonation of the diphosphate OH groups; major species at pH 7.3. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID24970669
CHEBI ID57823
MeSH IDM0350268

Synonyms (10)

Synonym
4-diphosphocytidyl-2c-methyl-d-erythritol
4-diphosphocytidyl-2-c-methylerythritol
cdp-methyl-d-erythritol
CHEBI:57823
cytidine 5'-{3-[(2r,3s)-2,3,4-trihydroxy-3-methylbutyl] diphosphate}
4-cdp-2-c-methyl-d-erythritol(2-)
5'-o-{[({[(2r,3s)-2,3,4-trihydroxy-3-methylbutyl]oxy}phosphinato)oxy]phosphinato}cytidine
4-cdp-2-c-methyl-d-erythritol dianion
Q27124977
[[(2r,3s,4r,5r)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [(2r,3s)-2,3,4-trihydroxy-3-methylbutyl] phosphate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
nucleotide-sugar oxoanionAny nucleotide-sugar in which one or more of the diphosphate OH groups has been deprotonated.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (9)

PathwayProteinsCompounds
Secondary Metabolites: Methylerythritol Phosphate and Polyisoprenoid Biosynthesis1121
Secondary Metabolites: Isoprenoid Biosynthesis (Nonmevalonate Pathway)818
MEP/DOXP Pathway819
superpathway of ergosterol biosynthesis II133
taxadiene biosynthesis (engineered)124
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP)1923
methylerythritol phosphate pathway I020
methylerythritol phosphate pathway II820
isoprene biosynthesis I122
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP)2639
taxadiene biosynthesis (engineered)1138
superpathway of ergosterol biosynthesis II135
methylerythritol phosphate pathway I934
methylerythritol phosphate pathway II1027

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's7 (77.78)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.02

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.02 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.41 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.02)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
cytidine diphosphate
Cytidine Diphosphate: Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.		210cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-diphosphate		Escherichia coli metabolite;
mouse metabolite
cytidine triphosphate
Cytidine Triphosphate: Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.		2.730cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
malachite green
malachite green: RN given refers to parent cpd; structure. malachite green : An organic chloride salt that is the monochloride salt of malachite green cation. Used as a green-coloured dye, as a counter-stain in histology, and for its anti-fungal properties in aquaculture.		2.0210organic chloride saltantibacterial agent;
antifungal drug;
carcinogenic agent;
environmental contaminant;
fluorochrome;
histological dye;
teratogenic agent
c.i. 42510
Rosaniline Dyes: Compounds that contain the triphenylmethane aniline structure found in rosaniline. Many of them have a characteristic magenta color and are used as COLORING AGENTS.. basic fuchsin : A four-component mixture of chemically related dyes comprising pararosanilin, rosanilin, magenta II and new fuchsin in varying amounts. rosanilin : A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the major constituents of Basic fuchsin, together with pararosanilin, magenta II and new fuchsin.		2.0210
erythritol
[no description available]		8.6390butane-1,2,3,4-tetrolantioxidant;
human metabolite;
plant metabolite
mevalonic acid
Mevalonic Acid: A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions.. mevalonic acid : A racemate composed of equimolar amounts of (R)- and (S)-mevalonic acid.. (R)-mevalonic acid : The (R)-enantiomer of mevalonic acid.		2103,5-dihydroxy-3-methylpentanoic acid
2-c-methylerythritol 4-phosphate
2-C-methylerythritol 4-phosphate: structure in first source		3.1150tetritol phosphateEscherichia coli metabolite
xylulose
[no description available]		210xyluloseEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
1-deoxy-2-pentulose
[no description available]		210deoxypentoseEscherichia coli metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Plasmodium vivax Malaria
[description not available]		02.1710
Malaria, Vivax
Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.		02.1710