4-dimethylaminomethylbenzylamine profile

4-dimethylaminomethylbenzylamine: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	193714
SCHEMBL ID	3972958
MeSH ID	M0042450

Synonyms (29)

Synonym
HMS1704G05
34490-85-2
n-[4-(aminomethyl)benzyl]-n,n-dimethylamine
EN300-13617
{4-[(dimethylamino)methyl]phenyl}methanamine
BB 0257854
4-dimethylaminomethyl-benzylamine
AKOS000200208
4-dimethylaminomethylbenzylamine
p-dimethylaminomethylbenzylamine
FT-0684192
1,4-benzenedimethanamine, n,n-dimethyl-
SCHEMBL3972958
4-(dimethylaminomethyl)phenylmethylamine
LYABQIBGTULUFB-UHFFFAOYSA-N
1-(4-(aminomethyl)phenyl)-n,n-dimethylmethanamine
J-523330
BS-13571
n-[4-(aminomethyl)benzyl]-n,n--dimethylamine
SY152150
CS-0197169
mfcd04107485
[4-(aminomethyl)phenyl]-n,n-dimethylmethanamine
AMY202100072
SB36734
AC9373
DTXSID10956029
1-[4-(aminomethyl)phenyl]-n,n-dimethylmethanamine
[4-[(dimethylamino)methyl]phenyl]methanamine

Bioassays (2)

Assay ID	Title	Year	Journal	Article
AID540299	A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis	2010	Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21	Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID588519	A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities	2011	Antiviral research, Sep, Volume: 91, Issue:3	High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	2 (33.33)	18.7374
1990's	2 (33.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.34 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.42 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.34)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
putrescine [no description available]	1.97	1	0	alkane-alpha,omega-diamine	antioxidant; fundamental metabolite
4-hydroxybenzylamine 4-hydroxybenzylamine: RN given refers to parent cpd	1.98	1	0	aromatic amine

Condition	Indicated	Relationship Strength	Studies	Trials
Encephalitis, Polio [description not available]	0	2.06	1	0
Poliomyelitis An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)	0	2.06	1	0

4-dimethylaminomethylbenzylamine

Description