Page last updated: 2024-12-07

4-diazoquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

4-Diazoquinone is a highly reactive and unstable compound that is rarely isolated in its pure form. It is typically generated in situ as an intermediate in organic synthesis. Its importance lies in its ability to undergo various reactions, including cycloadditions, electrophilic aromatic substitutions, and diazo coupling. The study of 4-diazoquinone focuses on its unique reactivity, potential applications in organic synthesis, and its role in the development of novel synthetic methodologies.'

4-diazoquinone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID79130
CHEMBL ID303169
MeSH IDM0157109

Synonyms (20)

Synonym
4-diazocyclohexa-2,5-dien-1-one
p-benzoquinone diazide
2,5-cyclohexadien-1-one, 4-diazo-
4-diazo-2,5-cyclohexadien-1-one
brn 1859770
p-diazoquinone
1,4-benzoquinone diazide
ccris 1275
p-quinone diazide
4-diazoquinone
quinone diazide
CHEMBL303169
932-97-8
AKOS006374055
4-diazoniophenolate
WTQZSMDDRMKJRI-UHFFFAOYSA-N
p-diazoniophenolate
4-diazocyclohexa-2,5-dienone
DTXSID00918611
p-benzochinondiazid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID23162Half-life period was determined at 20 degree Celsius at UV lambdamax nm of 348 (44000); Stable1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor.
AID71567Inhibition of [3H]GABA binding to Gamma-aminobutyric acid (GABA-A) receptor isolated from rat brain homogenates at 5*10e-4 M1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor.
AID23151Half-life period was determined at 20 degree Celsius at UV lambdamax nm of 313 (23000); Stable1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Aryl diazo compounds and diazonium salts as potential irreversible probes of the gamma-aminobutyric acid receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]