Page last updated: 2024-11-12
4-aminopyridine-3-methanol
Description
4-aminopyridine-3-methanol: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
4-aminopyridine-3-methanol : An aminopyridine that is 4-aminopyridine which is substituted by a hydroxymethyl group at position 3. It is a potassium channel blocker which restores axonal conduction after spinal cord injury. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 10796739 |
| CHEBI ID | 149772 |
| SCHEMBL ID | 1930789 |
| MeSH ID | M0544867 |
Synonyms (27)
| Synonym |
|---|
| 138116-34-4 |
| 4-aminopyridine-3-methanol |
| (4-aminopyridin-3-yl)methanol |
| (4-amino-pyridin-3-yl)-methanol |
| FT-0655323 |
| 4-ap-3-meoh |
| 4-amino-3-(hydroxymethyl)pyridine |
| 4-amino-3-pyridinemethanol , |
| CHEBI:149772 |
| AKOS005255261 |
| PB14435 |
| 3-pyridinemethanol, 4-amino- |
| AM20120561 |
| WNBVEYMTVDMSFZ-UHFFFAOYSA-N |
| 4-amino-3-hydroxymethylpyridine |
| SCHEMBL1930789 |
| W-205513 |
| TS-01636 |
| (4-amino-3-pyridinyl)methanol |
| DTXSID10444916 |
| (4-amino-pyridin-3-yl)-methanol, aldrichcpr |
| mfcd06203066 |
| CS-0044077 |
| (4-amino-pyridin-3-yl)methanol |
| 3-(4-hydroxyphenyl)propionicacidn-hydroxysuccinimideester |
| nsc790506 |
| nsc-790506 |
Roles (1)
| Role | Description |
|---|
| potassium channel blocker | An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (3)
| Class | Description |
|---|
| aminopyridine | Compounds containing a pyridine skeleton substituted by one or more amine groups. |
| aromatic amine | An amino compound in which the amino group is linked directly to an aromatic system. |
| aromatic primary alcohol | Any primary alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 18.36
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 18.36 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 5.12 (4.65) | | Search Engine Demand Index | 10.37 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |