Substance | Relationship Strength | Studies | Trials | Classes | Roles |
pentachlorophenol PENTA: structure given in first source | 1.98 | 1 | 0 | aromatic fungicide; chlorophenol; organochlorine pesticide; pentachlorobenzenes | human xenobiotic metabolite |
bis(4-hydroxyphenyl)sulfone bis(4-hydroxyphenyl)sulfone: structure and RN in first source. 4,4'-sulfonyldiphenol : A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups. | 2.17 | 1 | 0 | bisphenol; sulfone | endocrine disruptor; metabolite |
isatin tribulin: endogenous MONOAMINE OXIDASE inhibitory activity extractable into ethyl acetate found in brain and many mammalian tissues and fluids; ISATIN is a major component; produced in excess following alcohol withdrawal; | 2.06 | 1 | 0 | indoledione | EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite |
4-biphenylamine 4-biphenylamine: used in detection of sulfates, & as a carcinogen in cancer research; RN given refers to parent cpd; structure. biphenyl-4-amine : An aminobiphenyl that is biphenyl substituted by an amino group at position 4. | 2.06 | 1 | 0 | aminobiphenyl | carcinogenic agent |
4-benzylphenol 4-benzylphenol: metabolite of diphenylmethane; RN given refers to parent cpd | 2.17 | 1 | 0 | | |
4-cumylphenol [no description available] | 2.17 | 1 | 0 | diarylmethane | |
4-phenoxyphenol [no description available] | 2.17 | 1 | 0 | phenoxyphenol | |
4-hydroxybenzophenone 4-hydroxybenzophenone: RN given refers to parent cpd | 2.17 | 1 | 0 | benzophenones | |
3-aminobiphenyl 3-aminobiphenyl: structure given in first source | 2.06 | 1 | 0 | | |
bis(4-oxyphenyl)sulfide 4,4'-thiodiphenol: structure in first source | 2.17 | 1 | 0 | phenols | |
hypochlorous acid Hypochlorous Acid: An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.. hypochlorous acid : A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water. | 2.21 | 1 | 0 | chlorine oxoacid; reactive oxygen species | EC 2.5.1.18 (glutathione transferase) inhibitor; EC 3.1.1.7 (acetylcholinesterase) inhibitor; human metabolite |
nitroscanate [no description available] | 1.98 | 1 | 0 | | |
ro 09-1437 cyclothialidine: a DNA gyrase inhibitor; isolated from Streptomyces filipinensis; MF C26-H35-N5-O12-S; structure in first source | 2.17 | 1 | 0 | peptide | |
4-aminostilbene 4-aminostilbene: RN given refers to cpd without isomeric designation | 2.06 | 1 | 0 | | |
thiourea Thiourea: A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.. thiourea : The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur. | 1.98 | 1 | 0 | one-carbon compound; thioureas; ureas | antioxidant; chromophore |
novobiocin Novobiocin: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189). novobiocin : A coumarin-derived antibiotic obtained from Streptomyces niveus. | 2.17 | 1 | 0 | carbamate ester; ether; hexoside; hydroxycoumarin; monocarboxylic acid amide; monosaccharide derivative; phenols | antibacterial agent; antimicrobial agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor; Escherichia coli metabolite; hepatoprotective agent |