| Assay ID | Title | Year | Journal | Article |
|---|
| AID1604535 | Binding affinity to GABA-A alpha2 (unknown origin) assessed as increase in induced current relative to control | | | |
| AID1604530 | Binding affinity to GABA-A alpha3 (unknown origin) | | | |
| AID1604529 | Binding affinity to GABA-A alpha1 (unknown origin) | | | |
| AID601106 | Displacement of [3H]flunitrazepam from benzodiazepine binding site GABAA alpha2beta3gamma2 receptor expressed in Sf9 cells after 1 hr | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| AID601111 | Allosteric modulation of human GABAA alpha3beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at holding potential of -60mV by two-electrode voltage-clamp electrophysiology assay relative to 1 uM D | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| AID1604534 | Binding affinity to GABA-A alpha1 (unknown origin) assessed as increase in induced current relative to control | | | |
| AID1604528 | Binding affinity to GABA-A alpha2 (unknown origin) | | | |
| AID1604531 | Binding affinity to GABA-A alpha5 (unknown origin) | | | |
| AID601109 | Allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at holding potential of -60mV by two-electrode voltage-clamp electrophysiology assay relative to 1 uM D | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| AID601108 | Intrinsic clearance in human liver microsomes at 1 uM after 25 mins by LC/MS/MS analysis in presence of NADPH | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| AID1604537 | Binding affinity to GABA-A alpha5 (unknown origin) assessed as increase in induced current relative to control | | | |
| AID1604536 | Binding affinity to GABA-A alpha3 (unknown origin) assessed as increase in induced current relative to control | | | |
| AID601110 | Allosteric modulation of human GABAA alpha2beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as effect on GABA-induced chloride current at holding potential of -60mV by two-electrode voltage-clamp electrophysiology assay relative to 1 uM D | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| AID601107 | Solubility of the compound in DMSO by LC/MS/MS method | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Development and SAR of functionally selective allosteric modulators of GABAA receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |