Page last updated: 2024-12-09

4-amino-3-phenyl-1h-1,2,4-triazole-5(4h)-thione

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-amino-3-phenyl-1H-1,2,4-triazole-5(4H)-thione: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID737082
CHEMBL ID2016643
SCHEMBL ID1774028
MeSH IDM000607042

Synonyms (28)

Synonym
BB 0217973
22706-11-2
4-amino-5-phenyl-4h-[1,2,4]triazole-3-thiol
AN-153/14987002
4-amino-5-phenyl-4h-1,2,4-triazole-3-thiol
inchi=1/c8h8n4s/c9-12-7(10-11-8(12)13)6-4-2-1-3-5-6/h1-5h,9h2,(h,11,13
4-amino-5-phenyl-4h-1,2,4-triazole-3-thiol, 97%
STK408351
AKOS000269025
4-amino-3-phenyl-1h-1,2,4-triazole-5-thione
F0311-0776
AKOS004904244
3h-1,2,4-triazole-3-thione, 4-amino-2,4-dihydro-5-phenyl-
21089-45-2
CHEMBL2016643
9G-441S
SCHEMBL1774028
OKNHZPGPLNUEPC-UHFFFAOYSA-N
4h-1,2,4-triazole-3-thiol, 4-amino-5-phenyl-
DTXSID30177234
mfcd00269264
4-amino-3-phenyl-1,2,4-triazol-5-thione
3h-1,2,4-triazole-3-thione,4-amino-2,4-dihydro-5-phenyl-
4-amino-3-phenyl-1h-1,2,4-triazole-5(4h)-thione
4-amino-5-phenyl-4(h)-1,2,4-triazole-3-thiol
EN300-16512
F75331
Z55981942
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID656871Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
Thiosemicarbazone fragment embedded within 1,2,4-triazole ring as inhibitors of Entamoeba histolytica.
AID656870Antiamnesic activity against Entamoeba histolytica HM-1:IMSS trophozoites after 72 hrs by microdilution method2012Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
Thiosemicarbazone fragment embedded within 1,2,4-triazole ring as inhibitors of Entamoeba histolytica.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]