Compounds > 4,6-dibromo-2-(2',4'-dibromo)phenoxyanisole
Page last updated: 2024-11-12

4,6-dibromo-2-(2',4'-dibromo)phenoxyanisole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4,6-dibromo-2-(2',4'-dibromo)phenoxyanisole: a brominated compound, detected in the blubber of dolphins and other marine mammals from Queensland (northeast Australia) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID15884894
CHEMBL ID220432
MeSH IDM0446543

Synonyms (10)

Synonym
CHEMBL220432
benzene, 1,5-dibromo-3-(2,4-dibromophenoxy)-2-methoxy-
96920-28-4
2'-methoxy-2,3',4,5'-tetrabromodiphenyl ether
2'-meo-bde-68
NVNCBGPDUILJTG-UHFFFAOYSA-N
1,5-dibromo-3-(2,4-dibromophenoxy)-2-methoxybenzene
DTXSID60579121
2meo-bde68
4,6-dibromo-2-(2',4'-dibromo)phenoxyanisole
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (20)

Assay IDTitleYearJournalArticle
AID1324846Antimicrobial activity against Enterococcus faecium ATCC 51299 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID280396Antibacterial activity against Bacillus subtilis at 1 ug/disk after 24 hrs by agar-plate diffusion assay2007Journal of natural products, Mar, Volume: 70, Issue:3
Polybrominated diphenyl ethers from the Indonesian sponge Lamellodysidea herbacea.
AID280398Antibacterial activity against Bacillus subtilis at 10 ug/disk after 24 hrs by agar-plate diffusion assay2007Journal of natural products, Mar, Volume: 70, Issue:3
Polybrominated diphenyl ethers from the Indonesian sponge Lamellodysidea herbacea.
AID1324845Antimicrobial activity against Enterococcus faecium ATCC 29212 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID1324843Antimicrobial activity against Staphylococcus aureus ATCC 29213 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID280397Antibacterial activity against Bacillus subtilis at 5 ug/disk after 24 hrs by agar-plate diffusion assay2007Journal of natural products, Mar, Volume: 70, Issue:3
Polybrominated diphenyl ethers from the Indonesian sponge Lamellodysidea herbacea.
AID670576Antibacterial activity against Pseudomonas syringae by paper disc assay method2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID335870Inhibition of cell division of Strongylocentrotus intermedius fertilized eggs2002Journal of natural products, Aug, Volume: 65, Issue:8
Two new minor polybrominated dibenzo-p-dioxins from the marine sponge Dysidea dendyi.
AID670577Antibacterial activity against Staphylococcus aureus by paper disc assay method2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID1324850Cytotoxicity against African green monkey BSC1 cells assessed as decrease in cell viability after 24 hrs by MTT assay2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID670573Cytotoxicity against human HL60 cells assessed as decrease in cell number after 24 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID670578Antibacterial activity against Bacillus subtilis by paper disc assay method2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID280395Antibacterial activity against Bacillus subtilis at 0.1ug/disk after 24 hrs by agar-plate diffusion assay2007Journal of natural products, Mar, Volume: 70, Issue:3
Polybrominated diphenyl ethers from the Indonesian sponge Lamellodysidea herbacea.
AID1324844Antimicrobial activity against Staphylococcus aureus ATCC 43300 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID670575Antibacterial activity against Escherichia coli by paper disc assay method2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID1324849Antimicrobial activity against Candida albicans ATCC 28517 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID670574Cytotoxicity against human U937 cells assessed as decrease in cell number after 24 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID1324847Antimicrobial activity against Escherichia coli ATCC 25922 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
AID670579Toxicity in brine shrimps2012Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14
Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea.
AID1324848Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 by CLSI M07-A9 method2016Journal of natural products, 07-22, Volume: 79, Issue:7
Polybrominated Diphenyl Ethers: Structure Determination and Trends in Antibacterial Activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.43 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
oxacillin
Oxacillin: An antibiotic similar to FLUCLOXACILLIN used in resistant staphylococci infections.. oxacillin : A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta.		2.1310penicillinantibacterial agent;
antibacterial drug
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.		2.0210pyrrole;
secondary amine
2,4,6-tribromoanisole
2,4,6-tribromoanisole: produced by O-methylation of its direct precursor, 2,4,6-tribromophenol, generally comes from sources in the winery environment		2.0210
vancomycin
Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.		2.1310glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
etoposide
[no description available]		2.0710beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
lissamine rhodamine b
lissamine rhodamine B: RN given refers to parent cpd; Lissamine Rhodamine B refers to Na salt		2.0210
gentamicin c1a
[no description available]		2.1310gentamycin C
3,5-dibromo-2-(2,4-dibromophenoxy)phenol
3,5-dibromo-2-(2,4-dibromophenoxy)phenol: isolated from the marine sponge Callyspongidae; inhibits contraction of smooth muscle in ileum; structure in first source		2.1310
amphotericin b
Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.		2.1310antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
ConditionIndicatedRelationship StrengthStudiesTrials