Page last updated: 2024-12-05

4,4'-dichlorobenzophenone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4,4'-Dichlorobenzophenone is a white, crystalline solid that is used as an intermediate in the synthesis of various chemical compounds, including pharmaceuticals, pesticides, and dyes. Its synthesis typically involves the Friedel-Crafts acylation of chlorobenzene with benzoyl chloride. 4,4'-Dichlorobenzophenone exhibits a wide range of biological activities, including antibacterial, antifungal, and anticancer properties. It is also known to be a photoinitiator, which means it can initiate polymerization reactions when exposed to ultraviolet light. Research on 4,4'-Dichlorobenzophenone focuses on its potential applications in various industries, particularly in the development of new pharmaceuticals and materials. Its diverse biological activities and photoinitiating properties make it a subject of interest for researchers in various fields.

4,4'-dichlorobenzophenone: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7034
CHEMBL ID1870191
CHEBI ID194706
SCHEMBL ID51827
MeSH IDM0045906

Synonyms (67)

Synonym
EN300-31834
p-dichlorobenzophenone
4,4'-dichlorobenzophenone (dbp)
di(4-chlorophenyl)ketone
einecs 202-030-1
nsc 8787
bis(p-chlorophenyl)ketone
benzophenone, 4,4'-dichloro-
ai3-03064
brn 0643345
dbp (van)
bis(4-chlorophenyl)ketone
wln: gr dvr dg
di(p-chlorophenyl)ketone
nsc-8787
nsc8787
p,p'-dichlorobenzophenone
dcbp
bis(4-chlorophenyl) ketone
methanone, bis(4-chlorophenyl)-
usaf do-4
bis(4-chlorophenyl)methanone
4,4'-dichlorobenzophenone
C06643
90-98-2
STK290986
4,4'-dichlorobenzophenone, 99%
NCGC00163933-01
AC-10278
AKOS000282714
BMSE000517
D1621
CHEBI:194706
4-4-dichlorobenzophenone
cas-90-98-2
dtxsid3037626 ,
tox21_302130
dtxcid1017626
NCGC00255637-01
bis(4-chlorophenyl)-methanone
4,4'-dbp
unii-3mtl0yc2q5
3mtl0yc2q5 ,
4-07-00-01376 (beilstein handbook reference)
FT-0617037
4,4-dichlorobenzophenone
AE-641/00433006
SCHEMBL51827
4,4'-dichloro-benzophenone
bis-(4-chloro-phenyl)-methanone
p,p-dichlorobenzophenone
bis(4-chlorophenyl)methanone #
W-100319
CHEMBL1870191
mfcd00000623
4,4;-dichlorobenzophenone
4,4 inverted exclamation mark -dichlorobenzophenone
4,4'-dichlorobenzophenone, purum, >=99.0% (gc)
4,4'-dbp, pestanal(r), analytical standard
4,4'-dichlorobenzophenone 10 microg/ml in cyclohexane
SY009660
Q4637048
4,4'-dichlorobenzophenone-d8
AS-11851
CS-W012634
HY-W011918
Z335453234
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzophenonesAny aromatic ketone in which the carbonyl group is bonded to 2 phenyl groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (5)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency47.28120.001022.650876.6163AID1224838; AID1224893
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency39.40960.003041.611522,387.1992AID1159552; AID1159555
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency64.27640.001530.607315,848.9004AID1224841; AID1224848; AID1224849; AID1259401; AID1259403
pregnane X nuclear receptorHomo sapiens (human)Potency21.68990.005428.02631,258.9301AID1346982
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.00280.010039.53711,122.0200AID588547
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (27.27)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.30

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.30 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index5.19 (4.65)
Search Engine Demand Index29.35 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.30)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]