Compounds > 4,4'-biphenyldicarboxylic acid
Page last updated: 2024-12-05

4,4'-biphenyldicarboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4,4'-biphenyldicarboxylic acid: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID13084
CHEMBL ID3593502
SCHEMBL ID69873
MeSH IDM0529718

Synonyms (59)

Synonym
biphenyl-4,4'-dicarboxylic acid
einecs 212-328-3
brn 0523308
nsc 60016
4,4'-biphenyl dicarboxylic acid
(1,1'-biphenyl)-4,4'-dicarboxylic acid
[1,4'-dicarboxylic acid
nsc-60016
p,p'-diphenic acid
4,4'-dicarboxybiphenyl
4,4'-bibenzoic acid
nsc60016
4,4'-diphenic acid
787-70-2
wln: qvr dr dvq
4,4'-biphenyldicarboxylic acid
usaf do-69
biphenyl-4,4'-dicarboxylic acid, 97%
OPREA1_519768
STK012281
4,4'-diphenyldicarboxylic acid
b1191 ,
4,4'-dibenzoic acid
4-(4-carboxyphenyl)benzoic acid
FT-0656177
AKOS000119440
A840924
A839493
84787-70-2
[1,1'-biphenyl]-4,4'-dicarboxylic acid
biphenyl-4,4-dicarboxylic acid
4,4'-bisbenzoic acid
4-09-00-03563 (beilstein handbook reference)
FT-0632956
F3096-1199
SCHEMBL69873
biphenyl-4.4'-dicarboxylic acid
DTXSID7061140
SY015816
biphenyl-4,4 inverted exclamation mark -dicarboxylic acid
mfcd00002554
W-104270
STR04514
PS-7561
AC-23047
CHEMBL3593502
biphenyl-4,4'-dicarboxylic acid, vetec(tm) reagent grade, 97%
biphenyl-4,4`-dicarboxylic acid
CS-W014653
biphenyl-4,4-dicarboxylicacid
fema 3005
YSWG150
Q2662185
CK2208
EN300-17943
5D8ABY24N2
sandalwood oil from santalum album l.
HY-W013937
Z57127884
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1235354Antifungal activity against Cochliobolus lunatus strain MUCL 38696 at 100 uM by growth based assay2015Bioorganic & medicinal chemistry, Aug-01, Volume: 23, Issue:15
Benzoic acid derivatives with improved antifungal activity: Design, synthesis, structure-activity relationship (SAR) and CYP53 docking studies.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's8 (72.73)24.3611
2020's2 (18.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 40.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index40.28 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.56 (4.65)
Search Engine Demand Index50.49 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (40.28)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
trifluoroethanol
Trifluoroethanol: A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.		2.1110fluoroalcohol
2-naphthoic acid
2-naphthoic acid: RN given refers to parent cpd. 2-naphthoic acid : A naphthoic acid that is naphthalene carrying a carboxy group at position 2.		2.1110naphthoic acidmouse metabolite;
xenobiotic metabolite
terephthalic acid
terephthalic acid: RN given refers to 1,4-benzenedicarboxylic acid. terephthalic acid : A benzenedicarboxylic acid carrying carboxy groups at positions 1 and 4. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and isophthalic acids.		2.1110benzenedicarboxylic acid
4-fluorobenzoic acid
[no description available]		2.1110fluorobenzoic acidbacterial xenobiotic metabolite
2,6-naphthalenedicarboxylic acid
[no description available]		2.0510dicarboxylic acid
uranium
Uranium: A radioactive element of the actinide series of metals. It has an atomic symbol U, atomic number 92, and atomic weight 238.03. U-235 is used as the fissionable fuel in nuclear weapons and as fuel in nuclear power reactors.		2.0810actinoid atom;
f-block element atom;
monoatomic uranium
alkenes
[no description available]		2.0810
azides
Azides: Organic or inorganic compounds that contain the -N3 group.. azide : Any nitrogen molecular entity containing the group -N3.		2.1110pseudohalide anionmitochondrial respiratory-chain inhibitor
1-phenyl-2,2,2-trifluoroethanol
1-phenyl-2,2,2-trifluoroethanol: structure in first source		2.1110
proline
Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.		2.1110amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
ethyl cinnamate
ethyl cinnamate: a pine weevil antifeedant; structure in first source		2.1110alkyl cinnamate;
ethyl ester
stilbenes
Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.		2.0510stilbene
curcumin
Curcumin: A yellow-orange dye obtained from tumeric, the powdered root of CURCUMA longa. It is used in the preparation of curcuma paper and the detection of boron. Curcumin appears to possess a spectrum of pharmacological properties, due primarily to its inhibitory effects on metabolic enzymes.. curcumin : A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.		2.4110aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol		anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger
ConditionIndicatedRelationship StrengthStudiesTrials
Hepatocellular Carcinoma
[description not available]		02.4110
Cancer of Liver
[description not available]		02.4110
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.		02.4110
Liver Neoplasms
Tumors or cancer of the LIVER.		02.4110