Page last updated: 2024-12-07

4-(rhamnosyloxy)phenylacetonitrile

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-(rhamnosyloxy)phenylacetonitrile: from roasted seeds of Moringa oleifera; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
MoringagenusA plant genus of the family Moringaceae, order Capparales, subclass Dilleniidae, class Magnoliopsida.[MeSH]Moringaceae[no description available]

Cross-References

ID SourceID
PubMed CID129556
CHEMBL ID446981
CHEBI ID191636
SCHEMBL ID4652379
MeSH IDM0166705

Synonyms (16)

Synonym
4-(alpha-l-rhamnosyloxy)phenylacetonitrile
benzeneacetonitrile, 4-((6-deoxy-alpha-l-mannopyranosyl)oxy)-
4-((6-deoxy-alpha-l-mannopyranosyl)oxy)benzeneacetonitrile
4-(rhamnosyloxy)phenylacetonitrile
CHEMBL446981
122001-32-5
2-[4-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]acetonitrile
CHEBI:191636
niazirin
niazirine
SCHEMBL4652379
DTXSID60153465
4(alpha-l-rhamnosyloxy) phenylacetonitrile
2-[4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphenyl]acetonitrile
AKOS040762118
2-(4-(((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)phenyl)acetonitrile
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
glycosideA glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID502184Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated 30 mins prior to LPS challenge2010Bioorganic & medicinal chemistry, Sep-01, Volume: 18, Issue:17
Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits.
AID502185Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 5 uM incubated 30 mins prior to LPS challenge2010Bioorganic & medicinal chemistry, Sep-01, Volume: 18, Issue:17
Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits.
AID337326Hypotensive activity against normotensive anesthetized Wistar rat assessed as reduction in mean arterial blood pressure up to 5 ug/kg, iv1994Journal of natural products, Sep, Volume: 57, Issue:9
Isolation and structure elucidation of new nitrile and mustard oil glycosides from Moringa oleifera and their effect on blood pressure.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.01

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.01 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.01)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]