Compounds > 3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolinyl)methyl-4h-5,6-dihydro-1,2,4-oxadiazine
Page last updated: 2024-12-07

3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolinyl)methyl-4h-5,6-dihydro-1,2,4-oxadiazine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

CH 141: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID132839
SCHEMBL ID11307085
MeSH IDM0132820

Synonyms (13)

Synonym
pthiqdo
isoquinoline, 2-((5,6-dihydro-3-phenyl-2h-1,2,4-oxadiazin-6-yl)methyl)-1,2,3,4-tetrahydro-
ch-141 ,
ch 141
3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolyl)methyl-4h-5,6-dihydro-1,2,4-oxadiazine
3-phenyl-6-(1,2,3,4-tetrahydro-2-isoquinolinyl)methyl-4h-5,6-dihydro-1,2,4-oxadiazine
78279-88-6
2-[(3-phenyl-5,6-dihydro-2h-1,2,4-oxadiazin-6-yl)methyl]-1,2,3,4-tetrahydroisoquinoline
6-(3,4-dihydro-1h-isoquinolin-2-ylmethyl)-3-phenyl-5,6-dihydro-2h-1,2,4-oxadiazine
SCHEMBL11307085
DTXSID40999621
6-((3,4-dihydroisoquinolin-2(1h)-yl)methyl)-3-phenyl-5,6-dihydro-2h-1,2,4-oxadiazine
AKOS040751128

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Rate of absorption proved to be significantly higher compared to that of elimination."( Pharmacokinetic study of a new 1,2,4-oxadiazine derivative in rat.
Küttel, S; Mezei, J; Rácz, I, )		0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.37 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.37)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
ConditionIndicatedRelationship StrengthStudiesTrials