| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
chloroacetaldehyde
[no description available] | 1.96 | 1 | 0 | organochlorine compound | |
acetaldehyde
Acetaldehyde: A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.. acetaldehyde : The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.. aldehyde : A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.. acetyl group : A group, formally derived from acetic acid by dehydroxylation, which is fundamental to the biochemistry of all forms of life. When bound to coenzyme A, it is central to the metabolism of carbohydrates and fats. | 1.96 | 1 | 0 | aldehyde | carcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent |
methane
Methane: The simplest saturated hydrocarbon. It is a colorless, flammable gas, slightly soluble in water. It is one of the chief constituents of natural gas and is formed in the decomposition of organic matter. (Grant & Hackh's Chemical Dictionary, 5th ed). methane : A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC). | 1.95 | 1 | 0 | alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound | bacterial metabolite;
fossil fuel;
greenhouse gas |
cytosine
[no description available] | 1.96 | 1 | 0 | aminopyrimidine;
pyrimidine nucleobase;
pyrimidone | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
uridine
[no description available] | 4 | 14 | 0 | uridines | drug metabolite;
fundamental metabolite;
human metabolite |
cytidine
[no description available] | 8.09 | 5 | 0 | cytidines | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
ethylene oxide
Ethylene Oxide: A colorless and flammable gas at room temperature and pressure. Ethylene oxide is a bactericidal, fungicidal, and sporicidal disinfectant. It is effective against most micro-organisms, including viruses. It is used as a fumigant for foodstuffs and textiles and as an agent for the gaseous sterilization of heat-labile pharmaceutical and surgical materials. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p794). oxirane : A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. | 1.96 | 1 | 0 | gas molecular entity;
oxacycle;
saturated organic heteromonocyclic parent | allergen;
mouse metabolite;
mutagen |
deoxyuridine
[no description available] | 2.05 | 1 | 0 | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
pseudouridine
[no description available] | 7.02 | 1 | 0 | pseudouridines | fundamental metabolite |
chloroethylene oxide
chloroethylene oxide: postulated metabolite of vinyl chloride; structure | 1.96 | 1 | 0 | organochlorine compound | |
1-methyladenosine
[no description available] | 1.96 | 1 | 0 | methyladenosine | human metabolite |
adenosine
quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit | 3.09 | 5 | 0 | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent |
2',3'-o-isopropylidene uridine
2',3'-O-isopropylidene uridine: structure given in first source | 1.98 | 1 | 0 | | |
5-methylcytosine
5-Methylcytosine: A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.. 5-methylcytosine : A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position. | 1.96 | 1 | 0 | methylcytosine;
pyrimidines | human metabolite |
1-methylinosine
1-methylinosine : Inosine carrying a methyl substituent at position 1 on the hypoxanthine ring. | 2.38 | 2 | 0 | inosines | metabolite |
5-methylcytidine
[no description available] | 2.52 | 2 | 0 | methylcytidine | |
1-methylguanosine
1-methylguanosine : Guanosine substituted with a methyl group at position N-1. | 2.38 | 2 | 0 | methylguanosine | metabolite |
n-methyladenosine
N-methyladenosine: is a inhibitor of cell differentiation. N(6)-methyladenosine : A methyladenosine compound with one methyl group attached to N(6) of the adenine nucleobase. | 2.45 | 2 | 0 | methyladenosine | |
n(6),n(6)-dimethyladenosine
N(6),N(6)-dimethyladenosine : A methyladenosine compound with two methyl groups attached to N(6) of the adenine nucleobase. | 2 | 1 | 0 | hydrocarbyladenosine | |
ribothymidine
ribothymidine : A methyluridine having a single methyl substituent at the 5-position on the uracil ring. | 2.15 | 1 | 0 | methyluridine | antigen;
Escherichia coli metabolite;
human metabolite |
thiouridine
Thiouridine: A photoactivable URIDINE analog that is used as an affinity label.. 4-thiouridine : A thiouridine in which the oxygen replaced by sulfur is that at C-4. | 2.05 | 1 | 0 | nucleoside analogue;
thiouridine | affinity label;
antimetabolite |
phosphoramidite
phosphoramidite: structure in first source. phosphoramidite : A compound with the general formula (RO)2PNR2. Phosphoramidites can be regarded as phosphites that have an NR2 instead of an OH group, or as amides of phosphorous acid. | 2.08 | 1 | 0 | | |
3-methylpseudouridine
3-methylpseudouridine: structure given in first source | 7.02 | 1 | 0 | carbohydrate derivative;
nucleobase-containing molecular entity | |
isoguanosine
[no description available] | 2 | 1 | 0 | | |
3-methylcytidine
[no description available] | 7.35 | 2 | 0 | methylcytidine | |
guanosine
ribonucleoside : Any nucleoside where the sugar component is D-ribose. | 2.68 | 3 | 0 | guanosines;
purines D-ribonucleoside | fundamental metabolite |
inosine
[no description available] | 2.38 | 2 | 0 | inosines;
purines D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
2'-o-methylguanosine
2'-O-methylguanosine : Guanosine with the hydrogen on the hydroxyl at position C-2' substituted with a methyl group. | 2.38 | 2 | 0 | methylguanosine | metabolite |
n(2),n(2)-dimethylguanosine
N(2),N(2)-dimethylguanosine: elevated levels in urine of cancer patients. N(2),N(2)-dimethylguanosine : A guanosine where the hydrogens of the amine group at C-2 are substituted by methyl groups. | 2.38 | 2 | 0 | methylguanosine | human metabolite |