Compounds > 3-methyl-4',6-dihydroxy-3',5'-dibromoflavone
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3-methyl-4',6-dihydroxy-3',5'-dibromoflavone

Description

3-methyl-4',6-dihydroxy-3',5'-dibromoflavone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID128600
SCHEMBL ID1447424
MeSH IDM0160758

Synonyms (22)

Synonym
3-methyl-4',6-dihydroxy-3',5'-dibromoflavone
emd 21388
4h-1-benzopyran-4-one, 2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-methyl-
6,4'-dihydroxy-3-methyl-3',5'-dibromoflavone
fl8 ,
DB01838
2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-methylchromen-4-one
SCHEMBL1447424
unii-41l058nwh3
emd-21388
104567-72-8
41l058nwh3 ,
4h-1-benzopyran-4-one,2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-methyl-
GKDYOXMZSXVKPP-UHFFFAOYSA-N
3',5'-dibrom-6,4'-dihydroxy-3-methylflavone
DTXSID40146557
2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-methyl-4h-chromen-4-one
3',5'-dibromo-3-methyl-6,4'-dihydroxyflavone
FT-0759121
Q27092969
4h-1-benzopyran-4-one, 2-(3,5-dibromo-4-hydroxyphenyl)-6-hydroxy-3-met hyl-
PD008736

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (15.38)18.7374
1990's11 (84.62)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
amiodarone[no description available]medium101-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
furosemide[no description available]medium10chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
triiodothyronine[no description available]medium802-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
sulfobromophthalein[no description available]medium102-benzofurans;
organobromine compound;
organosulfonic acid;
phenols		dye
thyroxine[no description available]medium1102-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine		antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone
alanine[no description available]medium10alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid		EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite
threonine[no description available]medium10amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenytoin[no description available]medium10imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
methimazole[no description available]medium101,3-dihydroimidazole-2-thionesantithyroid drug
triiodothyronine, reverse[no description available]medium103,3',5'-triiodothyronine;
amino acid zwitterion
salicylic acid[no description available]medium10monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
salicylates[no description available]medium10monohydroxybenzoateplant metabolite
iodine[no description available]medium10diatomic iodinenutrient
benzofurans[no description available]medium10
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Liver0low10
Cancer of the Liver0low10
Cancer, Hepatocellular0low10
Carcinoma, Hepatocellular0low10
Hepatic Cancer0low10
Hepatic Neoplasms0low10
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Liver Cancer0low10
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Neoplasms0low10
Neoplasms, Hepatic0low10
Neoplasms, Liver0low10
Pregnancy0low10

Research Highlights

Long-term Use (1)

ArticleYear
In vivo effects of flavonoid EMD 21388 on thyroid hormone secretion and metabolism in rats.
The American journal of physiology, Volume: 261, Issue: 2 Pt 1		1991
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (1)

ArticleYear
Drug competition for intracellular triiodothyronine-binding sites.
European journal of endocrinology, Volume: 130, Issue: 4		1994
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]