Compounds > 3-methoxybenzonitrile
Page last updated: 2024-12-06

3-methoxybenzonitrile

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-methoxybenzonitrile is an organic compound with the formula CH3OC6H4CN. It is a white solid that is soluble in organic solvents. 3-methoxybenzonitrile is used as an intermediate in the synthesis of pharmaceuticals and other fine chemicals. It can be synthesized by the reaction of 3-methoxyphenol with cyanogen bromide. 3-methoxybenzonitrile has been shown to exhibit a variety of biological activities, including antimicrobial, anti-inflammatory, and antioxidant effects. It is also a promising candidate for the development of new anticancer drugs. 3-methoxybenzonitrile is being studied for its potential use in a variety of applications, including the treatment of bacterial infections, inflammatory diseases, and cancer. It is also being investigated for its potential to enhance the performance of solar cells and other energy storage devices.'

3-methoxybenzonitrile: RN & N1 from 9th CI Form Index; RN given refers to unlabeled parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID73712
SCHEMBL ID103841
MeSH IDM0090271

Synonyms (40)

Synonym
EN300-16193
STL354589
nsc-225049
m-anisonitrile
benzonitrile, m-methoxy-
m-methoxybenzonitrile
3-methoxybenzonitrile
nsc225049
1527-89-5
m-cyanoanisole
benzonitrile, 3-methoxy-
m-methoxybenzontrile
inchi=1/c8h7no/c1-10-8-4-2-3-7(5-8)6-9/h2-5h,1h
3-methoxybenzonitrile, 98%
AKOS000198127
M1291
3-cyanoanisole
HMS1725P03
m-methoxybenzonitrile;benzonitrile, 3-methoxy-;benzonitrile, m-methoxy-
A21196
3-anisonitrile
3-cyano-anisole
uy5e89bbs6 ,
nsc 225049
unii-uy5e89bbs6
einecs 216-201-3
FT-0615990
AB00159
CS-M0746
SCHEMBL103841
PS-5266
5-methoxybenzonitrile
3-methoxy benzonitrile
AM86650
STR02155
AC-24362
DTXSID4074695
J-512785
mfcd00001801
Z54464103
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.80 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.55 (4.65)
Search Engine Demand Index28.68 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.		1.9510metal allergen;
nickel group element atom		epitope;
micronutrient
benzonitrile
benzonitrile : A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group.		1.9910benzenes;
nitrile
3-nitrobenzonitrile
[no description available]		1.9910
4-nitrobenzonitrile
4-nitrobenzonitrile: structure given in first source		1.9910
silver
Silver: An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.		2.0410copper group element atom;
elemental silver		Escherichia coli metabolite
4-methoxybenzonitrile
4-methoxybenzonitrile: RN given refers to parent cpd		2.6830
aluminum
Aluminum: A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.		1.9510boron group element atom;
elemental aluminium;
metal atom
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio
[description not available]		02.0610
Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)		02.0610