Page last updated: 2024-12-07

3-deaza-2'-deoxyadenosine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-deaza-2'-deoxyadenosine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID122636
CHEMBL ID3143904
SCHEMBL ID11021787
MeSH IDM0180446

Synonyms (18)

Synonym
78582-17-9
3-deaza-2'-deoxyadenosine
3-deaza-2'-da
1h-imidazo[4,5-c]pyridin-4-amine, 1-(2'-deoxy-.beta.-d-erythro-pentofuranosyl)-
(2r,3s,5r)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
4-amino-2-deoxyribofuranosylimidazo[4,5-c]pyridine
(2r,3s,5r)-5-(4-aminoimidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)oxolan-3-ol
1h-imidazo(4,5-c)pyridin-4-amine, 1-(2-deoxy-beta-d-erythro-pentofuranosyl)-
2'-deoxy-3-deazaadenosine
DTXSID00229178
SCHEMBL11021787
AC-32284
CHEMBL3143904
AKOS026670209
(2r,3s,5r)-5-(4-amino-1h-imidazo[4,5-c]pyridin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
1h-imidazo[4,5-c]pyridin-4-amine,1-(2-deoxy-b-d-erythro-pentofuranosyl)-
3-deaza-2/'-deoxyadenosine
PD019526
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID176933Dose required to produce an acute inflammatory response of the algal poly saccharide carrageenan into the pleural cavity of rat.1986Journal of medicinal chemistry, Jan, Volume: 29, Issue:1
Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents.
AID207136Compound was tested for inhibition of human sternal marrow cell (D98) growth at a concentration of 100 uM1986Journal of medicinal chemistry, Jan, Volume: 29, Issue:1
Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents.
AID139845Compound was tested for inhibition of mouse connective tissue cell (L) growth at a concentration of 100 uM1986Journal of medicinal chemistry, Jan, Volume: 29, Issue:1
Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents.
AID67457Inhibition of lymphocyte-mediated cytolysis at a concentration of 100 uM in [51Cr]- labelled EL4 leukemia cells1986Journal of medicinal chemistry, Jan, Volume: 29, Issue:1
Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.82 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.90 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]