Compounds > 3-chloro-4-methyl-5-hydroxy-2(5h)-furanone
Page last updated: 2024-12-06

3-chloro-4-methyl-5-hydroxy-2(5h)-furanone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-Chloro-4-methyl-5-hydroxy-2(5H)-furanone, also known as MX, is a naturally occurring furanone compound found in various plants, including Artemisia species. MX exhibits diverse biological activities, including antimicrobial, anticancer, and anti-inflammatory properties. Its synthesis involves various methods, such as the reaction of 2-chloro-4-methyl-5-hydroxyfuran with a base or the oxidation of 4-methyl-5-hydroxy-2(5H)-furanone. MX is a promising candidate for drug development due to its multifaceted biological activities. Research into its potential therapeutic applications continues, particularly in the areas of infectious diseases and cancer treatment.'
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3-chloro-4-methyl-5-hydroxy-2(5H)-furanone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID60552
SCHEMBL ID16245792
MeSH IDM0266774

Synonyms (14)

Synonym
2(5h)-furanone, 3-chloro-5-hydroxy-4-methyl-
ccris 5338
3-chloro-4-methyl-5-hydroxy-2(5h)-furanone
4-chloro-2-hydroxy-3-methyl-2h-furan-5-one
3-chloro-5-hydroxy-4-methyl-2(5h)-furanone
AKOS006279030
unii-4l8r69907j
112309-61-2
4l8r69907j ,
SCHEMBL16245792
NXYVXACYNRXBAI-UHFFFAOYSA-N
3-chloro-5-hydroxy-4-methylfuran-2(5h)-one
DTXSID30920727
Q27894328
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.03

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.03 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.82 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.03)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
3-methylcholanthrene
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.. 3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.		2.0110ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
chlorine
Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.		1.9910diatomic chlorine;
gas molecular entity		bleaching agent
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone
3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone: structure given in first source		2.4220butenolide
adenosine
quinquefolan B: isolated from roots of Panax quinquefolium L.; RN not in Chemline 10/87; RN from Toxlit		6.9910adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
3,4-(dichloro)-5-hydroxy-2(5h)-furanone
3,4-(dichloro)-5-hydroxy-2(5H)-furanone: structure given in first source		2.730
3-chloro-4-(chloromethyl)-5-hydroxy-2(5h)-furanone
3-chloro-4-(chloromethyl)-5-hydroxy-2(5H)-furanone: structure given in first source		2.730
ConditionIndicatedRelationship StrengthStudiesTrials
Cell Transformation, Neoplastic
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.		02.0110
Cocarcinogenesis
The combination of two or more different factors in the production of cancer.		02.0110
Abnormalities, Autosome
[description not available]		02.4220