Page last updated: 2024-12-06
3-benzoylpyridine
Description
3-benzoylpyridine is a heterocyclic compound with a benzoyl group attached to the pyridine ring at the 3-position. It has been investigated for its potential biological activities and synthetic applications. Studies have shown that 3-benzoylpyridine exhibits anti-inflammatory properties, potentially due to its ability to inhibit the production of pro-inflammatory cytokines. It is also known to act as a ligand for the aryl hydrocarbon receptor (AhR), a protein involved in regulating gene expression. 3-benzoylpyridine has been synthesized through various methods, including Friedel-Crafts acylation of pyridine with benzoyl chloride. Its importance stems from its potential as a lead compound for the development of new drugs with therapeutic applications. Research on 3-benzoylpyridine aims to elucidate its mechanism of action, optimize its biological properties, and explore its potential in medicinal chemistry.'
3-benzoylpyridine: decomposition product of the soman antidote HGG-12; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 21540 |
| SCHEMBL ID | 125431 |
| MeSH ID | M0121551 |
Synonyms (47)
| Synonym |
|---|
| AC-1855 |
| EN300-26771 |
| phenyl(3-pyridinyl)methanone |
| einecs 226-561-3 |
| brn 0120234 |
| nsc 13190 |
| 3-pyridyl phenyl ketone |
| wln: t6nj cvr |
| phenyl 3-pyridyl ketone |
| 5424-19-1 |
| 3-benzoylpyridine |
| nsc13190 |
| ketone, phenyl 3-pyridyl |
| nsc-13190 |
| methanone, phenyl-3-pyridinyl- |
| pyridine, 3-benzoyl- |
| inchi=1/c12h9no/c14-12(10-5-2-1-3-6-10)11-7-4-8-13-9-11/h1-9 |
| MAYBRIDGE3_000706 |
| IDI1_012093 |
| AC-907/25014300 |
| phenyl(pyridin-3-yl)methanone |
| B0305 |
| AKOS000281712 |
| HMS1433A02 |
| STK802511 |
| A830058 |
| phenyl(3-pyridyl)methanone;3-benzoylpyridine |
| BBL011708 |
| unii-2a1326450x |
| 2a1326450x , |
| 5-21-08-00572 (beilstein handbook reference) |
| FT-0615090 |
| FS-3267 |
| phenyl-3-pyridyl ketone |
| 3-benzoyl pyridine |
| SCHEMBL125431 |
| phenyl(3-pyridinyl)methanone # |
| W-105650 |
| 4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylicacid |
| DTXSID90202591 |
| mfcd00006394 |
| SY030036 |
| AMY6979 |
| O12042 |
| Q27254455 |
| CS-W019516 |
| Z234809824 |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 20.16
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 20.16 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.32 (4.65) | | Search Engine Demand Index | 15.26 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |