| ID Source | ID |
|---|---|
| PubMed CID | 7375 |
| CHEMBL ID | 1162293 |
| SCHEMBL ID | 39591 |
| MeSH ID | M0040232 |
| Synonym |
|---|
| 3-(trifluoromethyl)benzenamine |
| 3-aminobenzotrifluoride |
| usaf ma-4 |
| 98-16-8 |
| m-aminobenzal fluoride |
| 3-(trifluoromethyl)aniline |
| .alpha.,.alpha.-trifluoro-m-toluidine |
| m-amino-.alpha.,.alpha.-trifluorotoluene |
| benzenamine, 3-(trifluoromethyl)- |
| nsc-4540 |
| nsc4540 |
| toluene,.alpha.,.alpha.-trifluoro-, |
| m-(trifluoromethyl)aniline |
| m-aminobenzotrifluoride |
| 1-amino-3-(trifluoromethyl)benzene |
| m-toluidine, .alpha.,.alpha.,.alpha.-trifluoro- |
| inchi=1/c7h6f3n/c8-7(9,10)5-2-1-3-6(11)4-5/h1-4h,11h |
| 3-amino,alpha,alpha,alpha-trifluoro-toluene |
| NCGC00091738-01 |
| 3-amino-a,a,a-trifluorotoluene |
| m-toluidine, alpha,alpha,alpha-trifluoro- |
| nsc 4540 |
| m-amino-alpha,alpha,alpha-trifluorotoluene |
| ai3-07422 |
| brn 0387672 |
| ccris 2812 |
| 3-trifluoromethyl aniline |
| hsdb 4249 |
| m-abtf |
| un2948 |
| toluene, 3-amino-alpha,alpha,alpha-trifluoro- |
| alpha,alpha,alpha-trifluoro-m-toluidine |
| einecs 202-643-4 |
| 3-(trifluoromethyl)aniline, >=99% |
| m-trifluoromethylaniline |
| NCGC00091738-02 |
| AC-027 |
| A0434 |
| 3-trifluoromethylbenzenamine |
| 3-aminotrifluorotoluene |
| CHEMBL1162293 |
| 3-(trifluoromethyl)benzenaminium |
| AKOS000119177 |
| NCGC00091738-03 |
| 3-(trifluoromethyl)-aniline |
| NCGC00257044-01 |
| cas-98-16-8 |
| dtxsid9024512 , |
| tox21_303081 |
| dtxcid504512 |
| tox21_201909 |
| NCGC00259458-01 |
| 3-trifluoromethylaniline |
| m-amino trifluorotoluene |
| 2,4,6-trifluoro-3-methylbenzenamine |
| STK943763 |
| 3-trifluoromethyl-phenylamine |
| unii-z1rwm538yn |
| 3-trifluoromethylaniline [un2948] [poison] |
| 4-12-00-01843 (beilstein handbook reference) |
| z1rwm538yn , |
| ec 202-643-4 |
| FT-0628142 |
| AM20060820 |
| 3-(trifluoromethyl)phenylamine |
| 3-aminotrifluoromethylbenzene |
| AH-357/04334061 |
| 3-amino-.alpha.,.alpha.,.alpha.-trifluorotoluene |
| m-(trifluoromethyl)aniline [hsdb] |
| .alpha.,.alpha.,.alpha.-trifluoro-m-toluidine |
| m-amino-.alpha.,.alpha.,.alpha.-trifluorotoluene |
| flutamide impurity d [ep impurity] |
| amino-alpha,alpha,alpha-trifluorotoluene, 3- |
| 2,3,6-trifluoro-5-methyl-aniline |
| SCHEMBL39591 |
| 3-trifluoromethylanilin |
| 3-trifluoromethyl phenyl amine |
| 3-(tri-fluormethyl)aniline |
| 3-trifluromethylaniline |
| 3-trifluoromethyl-aniline |
| [3-(trifluoromethyl)phenyl]amine |
| 3-aminobenzo-trifluoride |
| 3-(trifluoromethyl)-benzenamine |
| 3trifluoromethylaniline |
| 3-(trifluormethyl)aniline |
| 3-trifloromethyl aniline |
| 3-trifluormethylaniline |
| meta-aminobenzotrifluoride |
| alpha, alpha, alpha-trifluoro-m-toluidine |
| 3-(trifluoro-methyl)aniline |
| meta-trifluoromethylaniline |
| 3-f3cc6h4nh2 |
| 3-aminobenzotriflouride |
| 3-(trifluor-methyl)aniline |
| 3-trifluoromethylbenzeneamine |
| 3(trifluoromethyl)aniline |
| 5-trifluoromethyl-aniline |
| 3-amino-benzotrifluoride |
| m-trifluoromethyl-aniline |
| 3-(trifluoromethyl)benzeneamine |
| 3-(trifluoromethyl) aniline |
| m-trifluoromethyl aniline |
| 3-trifluoromethylphenylamine |
| toluene, 3-amino-.alpha.,.alpha.,.alpha.-trifluoro-, |
| un 2948 |
| W-100091 |
| PS-8763 |
| 51R , |
| mfcd00007797 |
| F2190-0435 |
| CS-D1197 |
| 3-(trifluoromethyl)aniline, technical, >=90% (gc) |
| flutamide imp. d (ep); niflumic acid imp. c (ep); 3-(trifluoromethyl)aniline; flutamide impurity d; niflumic acid impurity c |
| Q424934 |
| A935951 |
| xnziqyhxpbhlra-uhfffaoysa-n |
| EN300-19104 |
| iskcxmwfgfwnba-uhfffaoysa-n |
| 3-aminobenzotrifluoride / 3-(trifluoromethyl)aniline |
| Z104472788 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 0.1259 | 0.0002 | 21.2231 | 8,912.5098 | AID588516 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 0.1259 | 0.0013 | 18.0743 | 39.8107 | AID926; AID938 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 70.7946 | 0.0054 | 28.0263 | 1,258.9301 | AID720659 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 44.6684 | 0.0010 | 19.4141 | 70.9645 | AID588537 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 24.5442 | 0.0237 | 23.2282 | 63.5986 | AID743222 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 41.3694 | 0.0391 | 47.5451 | 146.8240 | AID1224845 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 0.0200 | 0.0398 | 16.7842 | 39.8107 | AID995 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 44.6684 | 0.0023 | 19.5956 | 74.0614 | AID651743 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1350315 | Mutagenicity in Salmonella typhimurium TA1535 in presence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350323 | Mutagenicity in Salmonella typhimurium TA100 in absence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350322 | Mutagenicity in Salmonella typhimurium TA98 in absence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350321 | Mutagenicity in Salmonella typhimurium TA1537 in absence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350320 | Mutagenicity in Salmonella typhimurium TA1535 in absence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350316 | Mutagenicity in Salmonella typhimurium TA1537 in presence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350324 | Mutagenicity in Escherichia coli WP2uvrA in absence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350317 | Mutagenicity in Salmonella typhimurium TA98 in presence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID1350319 | Mutagenicity in Escherichia coli WP2uvrA in presence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| AID342464 | Dissociation constant, pKa of the compound | 2008 | Journal of medicinal chemistry, Aug-14, Volume: 51, Issue:15 | The many roles for fluorine in medicinal chemistry. |
| AID1350318 | Mutagenicity in Salmonella typhimurium TA100 in presence of S9 fraction by Ames test | 2018 | ACS medicinal chemistry letters, Feb-08, Volume: 9, Issue:2 | Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (27.19) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||