Compounds > 3,4-epoxy-3-methyl-1-butene
Page last updated: 2024-11-06

3,4-epoxy-3-methyl-1-butene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-ethenyl-2-methyloxirane: forms adducts with 2'-deoxyadenosine; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID92166
MeSH IDM0271721

Synonyms (28)

Synonym
nsc-48598
nsc48598
1838-94-4
2-methyl-2-vinyloxirane, 95%
nsc 48598
3,4-epoxy-3-methyl-1-butene
2-methyl-2-vinyloxirane
ccris 5685
2-ethenyl-2-methyloxirane
unii-o364aqj1k5
o364aqj1k5 ,
oxirane, 2-ethenyl-2-methyl-
isoprene monoxide
AKOS015903306
2-methyl-2-vinyl-oxirane
3,4-epoxy-3-methyl-1-butene, (+/-)-
2-vinylpropylene oxide
isoprene epoxide
1,2-epoxy-2-methyl-3-butene
mfcd00075225
J-800023
J-640425
4,4,4-3fmet-1-(2-furyl)-1,3-butandione
J-640426
Q27285260
DTXSID701031061
EN300-130159
Z1255379160

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" Subsequently, the kinetic parameters were incorporated into a physiologically-based pharmacokinetic model, and species differences regarding isoprene diepoxide levels were forecasted."( Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling.
Bogaards, JJ; Freidig, AP; van Bladeren, PJ, 2001)		0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.24

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.24 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.24)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
phenobarbital
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.		210barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
isoprene
isoprene: used in manufacture of ''synthetic'' rubber, butyl rubber; copolymer in production of elastomers; structure. isoprene : A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds.		3.2760alkadiene;
hemiterpene;
volatile organic compound		plant metabolite
pentane
Pentanes: Five-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives.. pentane : A straight chain alkane consisting of 5 carbon atoms.		3.2760alkane;
volatile organic compound		non-polar solvent;
refrigerant
cyclohexene oxide
cyclohexene oxide: inhibitor of epoxide hydrase; structure		1.9910
3,4-epoxy-1-butene
3,4-epoxy-1-butene: RN given refers to monomer		2.0210
2'-deoxyadenosine
2'-deoxyformycin A: RN not in Chemline 9/85; RN and structure given in first source		2.0610purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
pyrene
pyrene: structure in Merck Index, 9th ed, #7746. pyrene : An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.		210ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
ConditionIndicatedRelationship StrengthStudiesTrials
Chromosome-Defective Micronuclei
[description not available]		02.0210