3,4-epithiobutanenitrile

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

3,4-epithiobutanenitrile: thiirane occuring naturally in cruciferous vegetables; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	148821
CHEBI ID	183064
MeSH ID	M0120925

Synonyms (15)

Synonym
2-(thiiran-2-yl)acetonitrile
CHEBI:183064
1-cyano-2,3-epithiopropane
thiiraneacetonitrile
3,4-epithiobutanenitrile
thiiraneacetonitrile, (+-)-
(+-)-thiiraneacetonitrile
58130-93-1
76786-80-6
thiirane-2-acetonitrile
BKIZJNMVTRYGSW-UHFFFAOYSA-N
(cyanomethyl)thiirane
thiiraneacetonitrile, 9ci
(thiiran-2-yl)acetonitrile
DTXSID20973702

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

Class	Description
nitrile	A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it.
thiirane
epithionitrile
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (16.67)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (16.67)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (16.67%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (83.33%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
propane Propane: A three carbon alkane with the formula H3CCH2CH3.	3.03	4	alkane; gas molecular entity	food propellant
acrolein [no description available]	2.05	1	enal	herbicide; human xenobiotic metabolite; toxin
allyl cyanide TL 350: structure given in first source. allyl cyanide : An aliphatic nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an allyl group.	3.25	1	aliphatic nitrile; olefinic compound	antifeedant; neurotoxin; plant metabolite
acetylcysteine N-acetyl-L-cysteine : An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.	2.21	1	acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid	antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary
sinigrin sinigrin: glucosinate in mustard seeds etc.; RN given refers to parent cpd. sinigrin : An alkenylglucosinolic acid that consists of 1-thio-beta-D-glucopyranose having a 4-[(sulfooxy)imino]but-1-en-4-yl group attached to the anomeric sulfur.	3.25	1	alkenylglucosinolic acid

Condition	Relationship Strength	Studies
Benign Neoplasms [description not available]	3.48	2
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	3.48	2
Cancer of Liver [description not available]	2.11	1
Liver Neoplasms Tumors or cancer of the LIVER.	2.11	1
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.	2.11	1
Behavior Disorders [description not available]	3.06	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	3.06	1
Mental Disorders Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.	3.06	1

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