Page last updated: 2024-12-08

3,4-dihydro-2h-pyrrole-5-carboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3,4-dihydro-2H-pyrrole-5-carboxylic acid: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

1-pyrroline-2-carboxylic acid zwitterion : A zwitterion resulting from the transfer of a proton from the carboxy group to the nitrogen of 1-pyrroline-2-carboxylic acid; major species at pH 7.3. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

1-pyrroline-2-carboxylic acid : The product resulting from formal oxidation of DL-proline by loss of hydrogen from the nitrogen and from the carbon alpha to the carboxylic acid, with the formation of a C=N bond. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID440046
CHEMBL ID18591
CHEBI ID36761
CHEBI ID39785
SCHEMBL ID142379
MeSH IDM0053581

Synonyms (30)

Synonym
2h-pyrrole-5-carboxylic acid, 3,4-dihydro-
delta-1-pyrroline-2-carboxylate
3,4-dihydro-2h-pyrrole-5-carboxylic acid
CHEBI:36761 ,
3,4-dihydro-2h-pyrrolium-5-carboxylate
1-pyrroline-2-carboxylic acid
C03564
delta1-pyrroline 2-carboxylate
2139-03-9
1-pyrroline 2-carboxylate
DB02838
E49F4442-6DE1-4B39-852F-3E04DDDA9C15
delta1-pyroline-2-carboxylate
CHEMBL18591
pyrroline-5-carboxylate
SCHEMBL142379
CHEBI:39785
1-pyrroline-2-carboxylic acid zwitterion
3,4-dihydro-2h-pyrrole-5-carboxylicacid
DTXSID70175653
d1-pyrroline 2-carboxylic acid
delta1-pyrroline 2-carboxylic acid
d1-pyrroline 2-carboxylate
Q27093798
CS-0147985
HY-138354
PD007596
497H5RPL8F
1,2-didehydroproline
delta1-pyrroline-2-carboxylic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
1-pyrrolinecarboxylic acid
zwitterionA neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (15)

PathwayProteinsCompounds
Arginine and Proline Metabolism2047
D-Arginine and D-Ornithine Metabolism110
Prolidase Deficiency (PD)2047
Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)2047
Hyperprolinemia Type II2047
Hyperprolinemia Type I2047
Prolinemia Type II2047
Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)2047
Ornithine Aminotransferase Deficiency (OAT Deficiency)2047
Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency2047
Hyperornithinemia with Gyrate Atrophy (HOGA)2047
Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]2047
L-Arginine:Glycine Amidinotransferase Deficiency2047
D-arginine and D-ornithine metabolism09
Biochemical pathways: part I0466
Amino acid metabolism094

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]