Page last updated: 2024-12-05
3,4-dichloro-1-butene
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
3,4-dichloro-1-butene: RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 12971 |
CHEMBL ID | 3182884 |
SCHEMBL ID | 190697 |
MeSH ID | M0134071 |
Synonyms (40)
Synonym |
---|
ia19eyw12d , |
ccris 8555 |
ec 212-079-0 |
4-01-00-00772 (beilstein handbook reference) |
unii-ia19eyw12d |
1-butene, 3,4-dichloro- |
1,2-dichloro-3-butene |
3,4-dichlorobut-1-ene |
3,4-dichloro-1-butene |
3,4-dichlorobutene-1 |
1-butene, 3,4-dichloro-, (+-)- |
brn 1739135 |
hsdb 5751 |
einecs 212-079-0 |
760-23-6 |
inchi=1/c4h6cl2/c1-2-4(6)3-5/h2,4h,1,3h |
3,4-dichloro-1-butene, 98% |
D1072 |
NCGC00249032-01 |
NCGC00256397-01 |
dtxsid8022113 , |
cas-760-23-6 |
dtxcid902113 |
tox21_302814 |
tox21_201361 |
NCGC00258913-01 |
AKOS006220765 |
FT-0614245 |
SCHEMBL190697 |
1-butene, 3,4-dichloro-, (+/-)- |
3,4-dichlorobut-1-ene [hsdb] |
1,2-dichlorobut-3-ene |
CHEMBL3182884 |
mfcd00000947 |
2-undecynoicacidmethylester |
3,4-dichloro-1 -butene |
Q27280624 |
D89774 |
BS-23013 |
EN300-7426254 |
Research Excerpts
Dosage Studied
Excerpt | Relevance | Reference |
---|---|---|
"In dose-response analysis, regression analysis and hypothesis testing are the main tools of choice." | ( Reconsidering sufficient and optimal test design in acute toxicity testing. Jager, T, 2014) | 0.4 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Protein Targets (8)
Potency Measurements
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 22.2771 | 3.1890 | 29.8841 | 59.4836 | AID1224846 |
AR protein | Homo sapiens (human) | Potency | 28.4620 | 0.0002 | 21.2231 | 8,912.5098 | AID743035; AID743063 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 35.0065 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552; AID1159555 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 13.9363 | 0.0015 | 30.6073 | 15,848.9004 | AID1224841 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 31.3559 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 22.1112 | 0.0002 | 29.3054 | 16,493.5996 | AID743069; AID743075 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 63.0957 | 0.0010 | 19.4141 | 70.9645 | AID743191 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 0.7079 | 0.0237 | 23.2282 | 63.5986 | AID743223 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 2 (33.33) | 18.7374 |
1990's | 1 (16.67) | 18.2507 |
2000's | 1 (16.67) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.95
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (21.95) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |