Compounds > 3-(trimethylsilyl)propanesulfonic acid
Page last updated: 2024-11-10

3-(trimethylsilyl)propanesulfonic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-(trimethylsilyl)propanesulfonic acid: used as a hydrophobic probe for proton magnetic resonance studies of apolar sites on proteins; RN given refers to Na salt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5167273
CHEBI ID195173
SCHEMBL ID424021
MeSH IDM0054409

Synonyms (47)

Synonym
nsc-83558
AKOS003398568
3-(trimethylsilyl)-1-propane sulfonic acid, sodium salt
2039-96-5
sodium 3-sulfopropyltrimethylsilane
sodium 3-(trimethylsilyl)propane sulfonate
1-propanesulfonic acid, 3-(trimethylsilyl)-, sodium salt
3-(trimethylsilyl)propanesulfonic acid
dss sodium salt
sodium 3-(trimethylsilyl)propane-1-sulfonate
3-(trimethylsilyl)-1-propanesulfonic acid sodium salt
T1638
sodium 3-(trimethylsilyl)-1-propanesulfonate
sodium 2,2-dimethyl-2-silapentane-5-sulfonate
sodium;3-trimethylsilylpropane-1-sulonate
CHEBI:195173
1-propanesulfonic acid, 3-(trimethylsilyl)- (sodium salt)
BMSE000795
2,2-dimethyl-2-silapentane-5-sulfonate sodium salt
sodium 3-(trimethylsilyl)propane-1-sulphonate hydrate
nsc 83558
1-propanesulfonic acid, 3-(trimethylsilyl)-, sodium salt (1:1)
einecs 218-031-5
FT-0633987
AKOS015904499
c6h15nao3ssi
SCHEMBL424021
HWEXKRHYVOGVDA-UHFFFAOYSA-M
DTXSID7062118
mfcd00007537
J-511036
AS-71314
sodium3-(trimethylsilyl)propane-1-sulfonate
2,2-dimethyl-2-silapentane-5-sulfonic acid, sodium salt
S07485
D84158
sodium;3-trimethylsilylpropane-1-sulfonate
hematoporphyrindihydrochloride
3-trimethylsilyl-1-propanesulfonic acid sodium salt
trimethylsilylpropanesulfonic acid sodium salt, monohydrate
trimethylsilylpropanesulfonicacid,sodiumsalt
2,2-dimethyl-2-silapentane-5-sulfonic acid, sodium salt (dss)
2,2-dimethyl-2-silapentane-5-sulfonic acid sodium salt
996MF68A8L
sodium 2,2'-dimethyl-2-silapentane-5-sulfonate
sodium 4,4-dimethyl-4-silapentane-1-sulfonate
sodium 4,4-dimethyl-4-silapentanesulfonate

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Both synthetic mixtures and dosage forms were assayed."( A quantitative NMR protocol for the simultaneous analysis of atropine and obidoxime in parenteral injection devices.
Dubey, DK; Ganesan, K; Gupta, PK; Mazumder, A; Sharma, R; Vijayaraghavan, R, 2009)		0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
NMR chemical shift reference compoundAny compound that produces a peak used to reference an NMR spectrum during data pre-processing.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
organosulfonic acidAn organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.20 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
hydrogen
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.		2.4420elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
n-methylacetamide
N-methylacetamide: RN given refers to parent cpd. N-methylacetamide : A monocarboxylic acid amide that is the N-methyl derivative of acetamide.		2.1310acetamides;
monocarboxylic acid amide		metabolite
obidoxime chloride
Obidoxime Chloride: Cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.		2.0510
phenylphosphonic acid
phenylphosphonic acid: RN given refers to parent cpd; NM same as N1		1.9710benzenes
2-(n-morpholino)ethanesulfonic acid
2-(N-morpholino)ethanesulfonic acid: RN given refers to parent cpd. 2-(N-morpholino)ethanesulfonic acid : A Good's buffer substance, pKa = 6.15 at 20 degreeC.		2.0610MES;
organosulfonic acid;
zwitterion
atropine
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate : A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.		2.0510
triacetoneamine-n-oxyl
Triacetoneamine-N-Oxyl: Cyclic N-oxide radical functioning as a spin label and radiation-sensitizing agent.. 4-oxo-TEMPO : A member of the class of aminoxyls that is TEMPO carrying an oxo group at position 4.		2.0510aminoxyls;
piperidones		radical scavenger
silicon
Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].		1.9710carbon group element atom;
metalloid atom;
nonmetal atom
phosphocreatine
Phosphocreatine: An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996). phosphagen : Any of a group of guanidine or amidine phosphates that function as storage depots for high-energy phosphate in muscle with the purpose of regenerating ATP from ADP during muscular contraction.. N-phosphocreatine : A phosphoamino acid consisting of creatine having a phospho group attached at the primary nitrogen of the guanidino group.		2.3820phosphagen;
phosphoamino acid		human metabolite;
mouse metabolite
piperidines
Piperidines: A family of hexahydropyridines.		2.0510
amyloid beta-peptides
amyloid beta-protein (1-40): although acutely neurotoxic in both rat & monkey cerebral cortex, neuronal degeneration in primates resembles more closely to that found in Alzheimer's disease; amino acid sequence has been determined		2.0210
ConditionIndicatedRelationship StrengthStudiesTrials
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		01.9710
Muscle Relaxation
That phase of a muscle twitch during which a muscle returns to a resting position.		01.9710