Page last updated: 2024-12-07

3-(4-(3-(trifluoromethyl)-3h-diazirin-3-yl)phenyl)alanine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)alanine: a photoreactive cross-linking reagent; structure given in first source; RN given is for D-phenylalanine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID125845
CHEMBL ID601047
SCHEMBL ID15546958
MeSH IDM0131011

Synonyms (15)

Synonym
3-(4-(3-(trifluoromethyl)-3h-diazirin-3-yl)phenyl)alanine
tfmdazpa
(2r)-2-amino-3-[4-[3-(trifluoromethyl)diazirin-3-yl]phenyl]propanoic acid
CHEMBL601047
95758-95-5
(tmd)phe
d-phenylalanine, 4-(3-(trifluoromethyl)-3h-diazirin-3-yl)-
SCHEMBL15546958
DTXSID80914818
4-[3-(trifluoromethyl)-3h-diaziren-3-yl]phenylalanine
(2r)-2-amino-3-{4-[3-(trifluoromethyl)-3h-diazirin-3-yl]phenyl}propanoic acid
EN300-33235140
(r)-2-amino-3-(4-(3-(trifluoromethyl)-3h-diazirin-3-yl)phenyl)propanoic acid
TQP0876
hrgxdarrscsgog-mrvpvssysa-n
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID458473Activity at human T1R2/T1R3 expressed in HEK293T cells co-expressing Galpha-16-gust44 assessed as F340/F380 ratio at 1.25 mM2010Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3
Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives.
AID458472Activity at human T1R2/T1R3 expressed in HEK293T cells co-expressing Galpha-16-gust44 assessed as F340/F380 ratio at 1.25 mM in presence of T1R2/T1R3 antagonist lactisole2010Bioorganic & medicinal chemistry letters, Feb-01, Volume: 20, Issue:3
Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.11

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.11 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.11)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]