| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID443876 | Inhibition of ERK1/2 phosphorylation in PMA-stimulated human U937 cells at 50 uM after 3 hrs by Western blotting | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID248093 | Inhibitory concentration against HeLa cell colony formation; Range is 15-20 uM | 2005 | Journal of medicinal chemistry, Jul-14, Volume: 48, Issue:14
| Identification of novel extracellular signal-regulated kinase docking domain inhibitors. |
| AID443877 | Inhibition of Rsk1 phosphorylation in PMA-stimulated human U937 cells at 50 uM after 3 hrs by Western blotting | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID612541 | Inhibition of human recombinant MAOB by amplex red assay | 2011 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 21, Issue:16
| Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B. |
| AID443884 | Inhibition of JNK phosphorylation | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID1917380 | Inhibition of recombinant human MAO-B | 2022 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 76 | Design, synthesis, in-vitro, in-vivo and ex-vivo pharmacology of thiazolidine-2,4-dione derivatives as selective and reversible monoamine oxidase-B inhibitors. |
| AID443887 | Inhibition of recombinant ERK2-mediated myelin basic protein phosphorylation at 50 uM after 30 mins by SDS-PAGE | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID443888 | Cytotoxicity against human U937 cells assessed as cell viability up to 30 uM after 24 hrs by MTT assay | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID247896 | Inhibitory concentration against growth of A549 lung carcinoma cell | 2005 | Journal of medicinal chemistry, Jul-14, Volume: 48, Issue:14
| Identification of novel extracellular signal-regulated kinase docking domain inhibitors. |
| AID612542 | Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetry | 2011 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 21, Issue:16
| Structure-activity relationship and docking studies of thiazolidinedione-type compounds with monoamine oxidase B. |
| AID443882 | Inhibition of p38 phosphorylation in PMA-stimulated human U937 cells at 50 uM after 3 hrs by Western blotting | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID238115 | Dissociation constant for ERK2 kinase | 2005 | Journal of medicinal chemistry, Jul-14, Volume: 48, Issue:14
| Identification of novel extracellular signal-regulated kinase docking domain inhibitors. |
| AID501302 | Inhibition of human recombinant MAO-B after 15 mins | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17
| Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening. |
| AID443886 | Inhibition of ERK1/2 phosphorylation in EGF-stimulated human SKOV3 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID501303 | Inhibition of ERK in human HeLa cells | 2010 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 20, Issue:17
| Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening. |
| AID443883 | Inhibition of MEK phosphorylation | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| AID443885 | Inhibition of ERK1/2 phosphorylation in EGF-stimulated human OVCAR5 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21
| Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: development of potential substrate-specific ERK1/2 inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |